The NMDA receptor regulates integrin activation, ATP release and arterial thrombosis through store-operated Ca(2+) entry in platelets

INTRODUCTION: Platelet activation and thrombus formation is crucial for hemostasis, but also trigger arterial thrombosis. Calcium mobilization plays an important role in platelet activation, because many cellular processes depend on the level of intracellular Ca(2+) ([Ca(2+)](i)), such as integrin a...

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Detalles Bibliográficos
Autores principales: Reusswig, Friedrich, Yilmaz, Münteha, Brechtenkamp, Marius, Krueger, Irena, Metz, Lisa Maria, Klöcker, Nikolaj, Lammert, Eckhard, Elvers, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217778/
https://www.ncbi.nlm.nih.gov/pubmed/37252113
http://dx.doi.org/10.3389/fcvm.2023.1171831

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