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Mutation-Driven S100A8 Overexpression Confers Aberrant Phenotypes in Type 1 CALR-Mutated MPN

Numerous pathogenic CALR exon 9 mutations have been identified in myeloproliferative neoplasms (MPN), with type 1 (52bp deletion; CALR(DEL)) and type 2 (5bp insertion; CALR(INS)) being the most prevalent. Despite the universal pathobiology of MPN driven by various CALR mutants, it is unclear why dif...

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Detalles Bibliográficos
Autores principales:	Wang, Ying-Hsuan, Chen, Ying-Ju, Lai, Yi-Hua, Wang, Ming-Chung, Chen, Yi-Yang, Wu, Yu-Ying, Yang, Yao-Ren, Tsou, Hsing-Yi, Li, Chian-Pei, Hsu, Chia-Chen, Huang, Cih-En, Chen, Chih-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217897/ https://www.ncbi.nlm.nih.gov/pubmed/37240094 http://dx.doi.org/10.3390/ijms24108747

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