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Potential Role of the mTORC1-PGC1α-PPARα Axis under Type-II Diabetes and Hypertension in the Human Heart

Type-2 diabetes (T2DM) and arterial hypertension (HTN) are major risk factors for heart failure. Importantly, these pathologies could induce synergetic alterations in the heart, and the discovery of key common molecular signaling may suggest new targets for therapy. Intraoperative cardiac biopsies w...

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Detalles Bibliográficos
Autores principales:	Hang, Tianyu, Lumpuy-Castillo, Jairo, Goikoetxea-Usandizaga, Naroa, Azkargorta, Mikel, Aldámiz, Gonzalo, Martínez-Milla, Juan, Forteza, Alberto, Cortina, José M., Egido, Jesús, Elortza, Félix, Martínez-Chantar, Malu, Tuñón, José, Lorenzo, Óscar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218005/ https://www.ncbi.nlm.nih.gov/pubmed/37239977 http://dx.doi.org/10.3390/ijms24108629

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