Boosting the Antibacterial Activity of Azithromycin on Multidrug-Resistant Escherichia coli by Efflux Pump Inhibition Coupled with Outer Membrane Permeabilization Induced by Phenylalanine-Arginine β-Naphthylamide

The global spread of multidrug-resistant (MDR) bacteria increases the demand for the discovery of new antibiotics and adjuvants. Phenylalanine-arginine β-naphthylamide (PAβN) is an inhibitor of efflux pumps in Gram-negative bacteria, such as the AcrAB-TolC complex in Escherichia coli. We aimed to ex...

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Detalles Bibliográficos
Autores principales: Al-Marzooq, Farah, Ghazawi, Akela, Daoud, Lana, Tariq, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218020/
https://www.ncbi.nlm.nih.gov/pubmed/37240007
http://dx.doi.org/10.3390/ijms24108662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218020/
https://www.ncbi.nlm.nih.gov/pubmed/37240007
http://dx.doi.org/10.3390/ijms24108662

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