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UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS

Chronic rhinosinusitis (CRS) is a widespread disease with various symptoms. It is defined as an inflammation of the nasal mucosa and paranasal sinuses lasting for 12 weeks, with symptoms of nasal obstruction and/or congestion and facial pain and/or pressure as well as decreased sense of smell. Despi...

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Autores principales: Vrljičak, Antonela, Penezić, Ana, Gregurić, Tomislav, Grgić, Marko Velimir, Baudoin, Tomislav, Kalogjera, Livije
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218087/
https://www.ncbi.nlm.nih.gov/pubmed/37250669
http://dx.doi.org/10.20471/acc.2022.61.s4.8
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author Vrljičak, Antonela
Penezić, Ana
Gregurić, Tomislav
Grgić, Marko Velimir
Baudoin, Tomislav
Kalogjera, Livije
author_facet Vrljičak, Antonela
Penezić, Ana
Gregurić, Tomislav
Grgić, Marko Velimir
Baudoin, Tomislav
Kalogjera, Livije
author_sort Vrljičak, Antonela
collection PubMed
description Chronic rhinosinusitis (CRS) is a widespread disease with various symptoms. It is defined as an inflammation of the nasal mucosa and paranasal sinuses lasting for 12 weeks, with symptoms of nasal obstruction and/or congestion and facial pain and/or pressure as well as decreased sense of smell. Despite the widespread prevalence of the disease, the diagnosis and treatment of CRS are still not adequately developed, so many patients remain misdiagnosed. This study involved 150 patients who, according to EPOS guidelines, met the diagnosis of CRS without nasal polyposis. Each patient underwent a computerized tomography (CT) scan of the paranasal sinuses, which was evaluated according to the Lund-Mackay scoring system. Furthermore, patients completed a visual analog scale (VAS) score questionnaire which examined the severity of their symptoms. The aim of this study was to find an association between the degree of mucositis and the clinical symptoms reported by the patient. Our results showed a low positive correlation between nasal secretion and Lund-Mackay score for the bilateral ostiomeatal complex (OMC). Furthermore, a low positive correlation was found between the severity of reduced sense of smell and severity of anterior ethmoid and sphenoid sinusitis. The results demonstrated a low negative correlation between the severity of facial pain or pressure and the severity of inflammation of the anterior ethmoid and sphenoid sinus. The results of statistical testing did not show statistical differences in severity of subjective symptoms for almost all of the observed symptoms in persons with unilateral inflammation and persons without unilateral inflammation, except for cough. People who did not have unilateral inflammation had a more pronounced cough compared with people who had unilateral inflammation. However, these correlations were very mild and not clinically significant, so we cannot say that the distribution of sinusitis significantly affects the occurrence of characteristic symptoms in chronic rhinosinusitis.
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spelling pubmed-102180872023-05-27 UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS Vrljičak, Antonela Penezić, Ana Gregurić, Tomislav Grgić, Marko Velimir Baudoin, Tomislav Kalogjera, Livije Acta Clin Croat Original Scientific Papers Chronic rhinosinusitis (CRS) is a widespread disease with various symptoms. It is defined as an inflammation of the nasal mucosa and paranasal sinuses lasting for 12 weeks, with symptoms of nasal obstruction and/or congestion and facial pain and/or pressure as well as decreased sense of smell. Despite the widespread prevalence of the disease, the diagnosis and treatment of CRS are still not adequately developed, so many patients remain misdiagnosed. This study involved 150 patients who, according to EPOS guidelines, met the diagnosis of CRS without nasal polyposis. Each patient underwent a computerized tomography (CT) scan of the paranasal sinuses, which was evaluated according to the Lund-Mackay scoring system. Furthermore, patients completed a visual analog scale (VAS) score questionnaire which examined the severity of their symptoms. The aim of this study was to find an association between the degree of mucositis and the clinical symptoms reported by the patient. Our results showed a low positive correlation between nasal secretion and Lund-Mackay score for the bilateral ostiomeatal complex (OMC). Furthermore, a low positive correlation was found between the severity of reduced sense of smell and severity of anterior ethmoid and sphenoid sinusitis. The results demonstrated a low negative correlation between the severity of facial pain or pressure and the severity of inflammation of the anterior ethmoid and sphenoid sinus. The results of statistical testing did not show statistical differences in severity of subjective symptoms for almost all of the observed symptoms in persons with unilateral inflammation and persons without unilateral inflammation, except for cough. People who did not have unilateral inflammation had a more pronounced cough compared with people who had unilateral inflammation. However, these correlations were very mild and not clinically significant, so we cannot say that the distribution of sinusitis significantly affects the occurrence of characteristic symptoms in chronic rhinosinusitis. Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb 2022-10 /pmc/articles/PMC10218087/ /pubmed/37250669 http://dx.doi.org/10.20471/acc.2022.61.s4.8 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Original Scientific Papers
Vrljičak, Antonela
Penezić, Ana
Gregurić, Tomislav
Grgić, Marko Velimir
Baudoin, Tomislav
Kalogjera, Livije
UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS
title UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS
title_full UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS
title_fullStr UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS
title_full_unstemmed UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS
title_short UNILATERAL VS. DIFFUSE CHRONIC RHINOSINUSITIS
title_sort unilateral vs. diffuse chronic rhinosinusitis
topic Original Scientific Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218087/
https://www.ncbi.nlm.nih.gov/pubmed/37250669
http://dx.doi.org/10.20471/acc.2022.61.s4.8
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