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Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials
Sulfur-containing molecules have a long history of bioactivity, especially as antibacterial agents in the fight against infectious pathogens. Organosulfur compounds from natural products have been used to treat infections throughout history. Many commercially available antibiotics also have sulfur-b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218091/ https://www.ncbi.nlm.nih.gov/pubmed/37240003 http://dx.doi.org/10.3390/ijms24108659 |
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author | Blume, Lindsay Long, Timothy E. Turos, Edward |
author_facet | Blume, Lindsay Long, Timothy E. Turos, Edward |
author_sort | Blume, Lindsay |
collection | PubMed |
description | Sulfur-containing molecules have a long history of bioactivity, especially as antibacterial agents in the fight against infectious pathogens. Organosulfur compounds from natural products have been used to treat infections throughout history. Many commercially available antibiotics also have sulfur-based moieties in their structural backbones. In the following review, we summarize sulfur-containing antibacterial compounds, focusing on disulfides, thiosulfinates, and thiosulfonates, and opportunities for future developments in the field. |
format | Online Article Text |
id | pubmed-10218091 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102180912023-05-27 Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials Blume, Lindsay Long, Timothy E. Turos, Edward Int J Mol Sci Review Sulfur-containing molecules have a long history of bioactivity, especially as antibacterial agents in the fight against infectious pathogens. Organosulfur compounds from natural products have been used to treat infections throughout history. Many commercially available antibiotics also have sulfur-based moieties in their structural backbones. In the following review, we summarize sulfur-containing antibacterial compounds, focusing on disulfides, thiosulfinates, and thiosulfonates, and opportunities for future developments in the field. MDPI 2023-05-12 /pmc/articles/PMC10218091/ /pubmed/37240003 http://dx.doi.org/10.3390/ijms24108659 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Blume, Lindsay Long, Timothy E. Turos, Edward Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials |
title | Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials |
title_full | Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials |
title_fullStr | Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials |
title_full_unstemmed | Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials |
title_short | Applications and Opportunities in Using Disulfides, Thiosulfinates, and Thiosulfonates as Antibacterials |
title_sort | applications and opportunities in using disulfides, thiosulfinates, and thiosulfonates as antibacterials |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218091/ https://www.ncbi.nlm.nih.gov/pubmed/37240003 http://dx.doi.org/10.3390/ijms24108659 |
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