Cargando…
Inhibition of Replication Fork Formation and Progression: Targeting the Replication Initiation and Primosomal Proteins
Over 1.2 million deaths are attributed to multi-drug-resistant (MDR) bacteria each year. Persistence of MDR bacteria is primarily due to the molecular mechanisms that permit fast replication and rapid evolution. As many pathogens continue to build resistance genes, current antibiotic treatments are...
Autores principales: | Radford, Holly M., Toft, Casey J., Sorenson, Alanna E., Schaeffer, Patrick M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218098/ https://www.ncbi.nlm.nih.gov/pubmed/37240152 http://dx.doi.org/10.3390/ijms24108802 |
Ejemplares similares
-
Delineation of the Ancestral Tus-Dependent Replication Fork Trap
por: Toft, Casey J., et al.
Publicado: (2021) -
Overexpression of the Replicative Helicase in Escherichia coli Inhibits Replication Initiation and Replication Fork Reloading
por: Brüning, Jan-Gert, et al.
Publicado: (2016) -
The progression of replication forks at natural replication barriers in live bacteria
por: Moolman, M. Charl, et al.
Publicado: (2016) -
DNA Replication Control During Drosophila Development: Insights into the Onset of S Phase, Replication Initiation, and Fork Progression
por: Hua, Brian L., et al.
Publicado: (2017) -
Replication Stress-Induced Chromosome Breakage Is Correlated with Replication Fork Progression and Is Preceded by Single-Stranded DNA Formation
por: Feng, Wenyi, et al.
Publicado: (2011)