Cargando…

Metformin Resistance Is Associated with Expression of Inflammatory and Invasive Genes in A549 Lung Cancer Cells

Metformin, the most commonly used drug for type 2 diabetes, has recently been shown to have beneficial effects in patients with cancer. Despite growing evidence that metformin can inhibit tumor cell proliferation, invasion, and metastasis, studies on drug resistance and its side effects are lacking....

Descripción completa

Detalles Bibliográficos
Autores principales:	Seo, Dong Soo, Joo, Sungmin, Baek, Seungwoo, Kang, Jaehyeon, Kwon, Taeg Kyu, Jang, Younghoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218153/ https://www.ncbi.nlm.nih.gov/pubmed/37239373 http://dx.doi.org/10.3390/genes14051014

Ejemplares similares

Metformin mediated microRNA-7 upregulation inhibits growth, migration, and invasion of non-small cell lung cancer A549 cells
por: Dong, Jingying, et al.
Publicado: (2020)

Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways
por: Morelli, Ana Paula, et al.
Publicado: (2021)

Activation of caspases and inhibition of ribosome biogenesis mediate antitumor activity of Chijongdan in A549 non-small lung cancer cells
por: Kim, Bo Geun, et al.
Publicado: (2014)

An important role for peroxiredoxin II in survival of A549 lung cancer cells resistant to gefitinib
por: Kwon, Taeho, et al.
Publicado: (2015)

Alpha-mangostin inhibits the migration and invasion of A549 lung cancer cells
por: Phan, Thi Kieu Trang, et al.
Publicado: (2018)

Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study
por: Wang, Yanyan, et al.
Publicado: (2009)

Cathepsin A knockdown decreases the proliferation and invasion of A549 lung adenocarcinoma cells
por: Hu, Bo, et al.
Publicado: (2020)

EGF Induces Migration Independent of EMT or Invasion in A549 Lung Adenocarcinoma Cells
por: Schelch, Karin, et al.
Publicado: (2021)

Inhibition of A549 Lung Cancer Cell Migration and Invasion by Ent-Caprolactin C via the Suppression of Transforming Growth Factor-β-Induced Epithelial—Mesenchymal Transition
por: Kim, So Young, et al.
Publicado: (2021)

Dendrotoxin-κ suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice
por: Jang, Soo Hwa, et al.
Publicado: (2011)

Gene expression profiling of cancer stem cell in human lung adenocarcinoma A549 cells
por: Seo, Dong-Cheol, et al.
Publicado: (2007)

PRDM14 mediates chemosensitivity and glycolysis in drug-resistant A549/cisplatin cells and their progenitor A549 human lung adenocarcinoma cells
por: He, Saifei, et al.
Publicado: (2021)

Anti-Inflammatory Effects of Ginsenoside Rg3 via NF-κB Pathway in A549 Cells and Human Asthmatic Lung Tissue
por: Lee, In-Seung, et al.
Publicado: (2016)

Effect of BIS depletion on HSF1-dependent transcriptional activation in A549 non-small cell lung cancer cells
por: Yun, Hye Hyeon, et al.
Publicado: (2018)

Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states
por: Kang, Hye Suk, et al.
Publicado: (2016)

Gomisin M2 alleviates psoriasis-like skin inflammation by inhibiting inflammatory signaling pathways
por: Kim, Namkyung, et al.
Publicado: (2021)

Neutrophil Extracellular Traps Facilitate A549 Cell Invasion and Migration in a Macrophage-Maintained Inflammatory Microenvironment
por: Zhang, Lemeng, et al.
Publicado: (2022)

Antiproliferative Effect of Aminoethyl-Chitooligosaccharide on Human Lung A549 Cancer Cells
por: Ngo, Dai Hung, et al.
Publicado: (2019)

Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells
por: Huang, Bo, et al.
Publicado: (2016)

CRTC2 promotes non‐small cell lung cancer A549 migration and invasion in vitro
por: Shi, Shaoqing, et al.
Publicado: (2017)

Retraction: Cyclooxygenase-2 mediates puerarin to inhibit the invasion and metastasis of lung cancer A549 cells
por: Zeng, Yun, et al.
Publicado: (2019)

Metformin inhibits the proliferation of A549/CDDP cells by activating p38 mitogen-activated protein kinase
por: WANG, YAJUN, et al.
Publicado: (2014)

Inhibitory effects of NSAID-conjugated SN-38 on the viability of A549 Non-small cell lung cancer cells
por: Kwon, Hae–Won, et al.
Publicado: (2023)

Cannabidiol Regulates PPARγ-Dependent Vesicle Formation as well as Cell Death in A549 Human Lung Cancer Cells
por: Park, Yoon-Jong, et al.
Publicado: (2022)

Mycelial Extract of Phellinus linteus Induces Cell Death in A549 Lung Cancer Cells and Elevation of Nitric Oxide in Raw 264.7 Macrophage Cells
por: Lee, Jong-Jin, et al.
Publicado: (2006)

Radix Tetrastigma hemsleyani flavone inhibits proliferation, migration, and invasion of human lung carcinoma A549 cells
por: Zhong, Liangrui, et al.
Publicado: (2016)

Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway
por: Jiang, Shulong, et al.
Publicado: (2016)

Invasive bronchial fibroblasts derived from asthmatic patients activate lung cancer A549 cells in vitro
por: Ryszawy, Damian, et al.
Publicado: (2018)

Effects of wogonoside on invasion and migration of lung cancer A549 cells and angiogenesis in xenograft tumors of nude mice
por: Yan, Yubo, et al.
Publicado: (2020)

Cadmium induces A549 cell migration and invasion by activating ERK
por: Zhai, Huijuan, et al.
Publicado: (2019)

STIM1 silencing inhibits the migration and invasion of A549 cells
por: Wang, Yadong, et al.
Publicado: (2017)

Cathepsin K inhibition induces Raptor destabilization and mitochondrial dysfunction via Syk/SHP2/Src/OTUB1 axis-mediated signaling
por: Seo, Seung Un, et al.
Publicado: (2023)

Similarities and Distinctions in the Effects of Metformin and Carbon Monoxide in Immunometabolism
por: Park, Jeongmin, et al.
Publicado: (2019)

Thrombin induces epithelial-mesenchymal transition via PAR-1, PKC, and ERK1/2 pathways in A549 cells
por: Song, Jeong Sup, et al.
Publicado: (2013)

Dual Cytotoxic Responses Induced by Treatment of A549 Human Lung Cancer Cells with Sweet Bee Venom in a Dose-Dependent Manner
por: Hwang, Yu-Na, et al.
Publicado: (2022)

Anti-Inflammatory Effects of the Novel PIM Kinase Inhibitor KMU-470 in RAW 264.7 Cells through the TLR4-NF-κB-NLRP3 Pathway
por: Baek, Hye Suk, et al.
Publicado: (2020)

Downregulation of HIF-2α Reverse the Chemotherapy Resistance of Lung Adenocarcinoma A549 Cells to Cisplatin
por: Gao, Zhao-jia, et al.
Publicado: (2018)

Screening miRNAs associated with resistance gemcitabine from exosomes in A549 lung cancer cells
por: Liang, Ai-Ling, et al.
Publicado: (2019)

Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells
por: Horibe, Sayo, et al.
Publicado: (2022)

Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells
por: Chan, Shun-Ming, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dogtsuk74dg5rsl2iaf9c2hqdh