Cargando…

Inflammation: The Link between Neural and Vascular Impairment in the Diabetic Retina and Therapeutic Implications

The etiology of diabetic retinopathy (DR) is complex, multifactorial and compromises all the elements of the retinal neurovascular unit (NVU). This diabetic complication has a chronic low-grade inflammatory component involving multiple inflammatory mediators and adhesion molecules. The diabetic mili...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramos, Hugo, Hernández, Cristina, Simó, Rafael, Simó-Servat, Olga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218195/ https://www.ncbi.nlm.nih.gov/pubmed/37240138 http://dx.doi.org/10.3390/ijms24108796

Ejemplares similares

Effects of the Topical Administration of Semaglutide on Retinal Neuroinflammation and Vascular Leakage in Experimental Diabetes
por: Simó, Rafael, et al.
Publicado: (2021)

Mechanisms of retinal neuroprotection of calcium dobesilate: therapeutic implications
por: Simó-Servat, Olga, et al.
Publicado: (2017)

Effect of Topical Administration of Somatostatin on Retinal Inflammation and Neurodegeneration in an Experimental Model of Diabetes
por: Hernández, Cristina, et al.
Publicado: (2020)

Genetics in Diabetic Retinopathy: Current Concepts and New Insights
por: Simó-Servat, Olga, et al.
Publicado: (2013)

Circulating Biomarkers of Diabetic Retinopathy: An Overview Based on Physiopathology
por: Simó-Servat, Olga, et al.
Publicado: (2016)

Usefulness of the Vitreous Fluid Analysis in the Translational Research of Diabetic Retinopathy
por: Simó-Servat, Olga, et al.
Publicado: (2012)

Neurovascular Unit: A New Target for Treating Early Stages of Diabetic Retinopathy
por: Simó, Rafael, et al.
Publicado: (2021)

Advanced Glycations End Products in the Skin as Biomarkers of Cardiovascular Risk in Type 2 Diabetes
por: Planas, Alejandra, et al.
Publicado: (2022)

Usefulness of Eye Fixation Assessment for Identifying Type 2 Diabetic Subjects at Risk of Dementia
por: Simó-Servat, Olga, et al.
Publicado: (2019)

New Insights into the Mechanisms of Action of Topical Administration of GLP-1 in an Experimental Model of Diabetic Retinopathy
por: Sampedro, Joel, et al.
Publicado: (2019)

Usefulness of Liquid Biopsy Biomarkers from Aqueous Humor in Predicting Anti-VEGF Response in Diabetic Macular Edema: Results of a Pilot Study
por: Udaondo, Patricia, et al.
Publicado: (2019)

Effects of Liposomal Formulation of Citicoline in Experimental Diabetes-Induced Retinal Neurodegeneration
por: Bogdanov, Patricia, et al.
Publicado: (2018)

Retinal Microperimetry: A Useful Tool for Detecting Insulin Resistance-Related Cognitive Impairment in Morbid Obesity
por: Ciudin, Andreea, et al.
Publicado: (2019)

Diabetic Retinopathy and Skin Tissue Advanced Glycation End Products Are Biomarkers of Cardiovascular Events in Type 2 Diabetic Patients
por: Planas, Alejandra, et al.
Publicado: (2021)

Molecular Implications of the PPARs in the Diabetic Eye
por: Ciudin, Andreea, et al.
Publicado: (2013)

Lowered cortistatin expression is an early event in the human diabetic retina and is associated with apoptosis and glial activation
por: Carrasco, Esther, et al.
Publicado: (2008)

Genetic Testing to Predict Weight Loss and Diabetes Remission and Long-Term Sustainability after Bariatric Surgery: A Pilot Study
por: Ciudin, Andreea, et al.
Publicado: (2019)

Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes
por: Bogdanov, Patricia, et al.
Publicado: (2018)

Efficacy of Insulin Titration Driven by SMS in Improving Glycemic Control in People with Type 2 Diabetes
por: Ortiz-Zúñiga, Ángel, et al.
Publicado: (2023)

The Gaze Fixation Assessed by Microperimetry: A Useful Tool for the Monitoring of the Cognitive Function in Patients with Type 2 Diabetes
por: Ortiz-Zúñiga, Ángel Michael, et al.
Publicado: (2021)

Iron Overload in Diabetic Retinopathy: A Cause or a Consequence of Impaired Mechanisms?
por: Ciudin, Andreea, et al.
Publicado: (2010)

Molecular Pathways in Prolactinomas: Translational and Therapeutic Implications
por: Biagetti, Betina, et al.
Publicado: (2021)

Neuroprotection as a Therapeutic Target for Diabetic Retinopathy
por: Hernández, Cristina, et al.
Publicado: (2016)

Update on Diagnosis and Treatment of Diabetic Retinopathy: A Consensus Guideline of the Working Group of Ocular Health (Spanish Society of Diabetes and Spanish Vitreous and Retina Society)
por: Corcóstegui, Borja, et al.
Publicado: (2017)

Transcriptomic Analysis Reveals That Retinal Neuromodulation Is a Relevant Mechanism in the Neuroprotective Effect of Sitagliptin in an Experimental Model of Diabetic Retinopathy
por: Ramos, Hugo, et al.
Publicado: (2022)

Phenotyping Type 2 Diabetes in Terms of Myocardial Insulin Resistance and Its Potential Cardiovascular Consequences: A New Strategy Based on (18)F-FDG PET/CT
por: Herance, José Raul, et al.
Publicado: (2022)

Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases
por: Sundstrom, Jeffrey M., et al.
Publicado: (2018)

Phagocytic Activity Is Impaired in Type 2 Diabetes Mellitus and Increases after Metabolic Improvement
por: Lecube, Albert, et al.
Publicado: (2011)

Beneficial Effects of Glucagon-Like Peptide-1 (GLP-1) in Diabetes-Induced Retinal Abnormalities: Involvement of Oxidative Stress
por: Ramos, Hugo, et al.
Publicado: (2020)

Advances in the Medical Treatment of Diabetic Retinopathy
por: Simó, Rafael, et al.
Publicado: (2009)

Insights into Insulin Resistance and Calcification in the Myocardium in Type 2 Diabetes: A Coronary Artery Analysis
por: Martín-Saladich, Queralt, et al.
Publicado: (2023)

Dapagliflozin protects neural and vascular dysfunction of the retina in diabetes
por: Luo, Qianyi, et al.
Publicado: (2022)

New Insights into Treating Early and Advanced Stage Diabetic Retinopathy
por: Simó, Rafael, et al.
Publicado: (2022)

What else can we do to prevent diabetic retinopathy?
por: Simó, Rafael, et al.
Publicado: (2023)

Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy
por: Ramos, Hugo, et al.
Publicado: (2022)

Topical ocular administration of DPP-IV inhibitors: a new approach for treating diabetes-induced retinal neurodegeneration
por: Simó, Rafael, et al.
Publicado: (2023)

Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy
por: Ramos, Hugo, et al.
Publicado: (2021)

The Retinal Pigment Epithelium: Something More than a Constituent of the Blood-Retinal Barrier—Implications for the Pathogenesis of Diabetic Retinopathy
por: Simó, Rafael, et al.
Publicado: (2010)

Minimum Effective Dose of DPP-4 Inhibitors for Treating Early Stages of Diabetic Retinopathy in an Experimental Model
por: Bogdanov, Patricia, et al.
Publicado: (2022)

Overexpression of Hemopexin in the Diabetic Eye: A new pathogenic candidate for diabetic macular edema
por: Hernández, Cristina, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_t9764canng3lr9milf38uf9b7s