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Nuclear DJ-1 Regulates DNA Damage Repair via the Regulation of PARP1 Activity

DNA damage and defective DNA repair are extensively linked to neurodegeneration in Parkinson’s disease (PD), but the underlying molecular mechanisms remain poorly understood. Here, we determined that the PD-associated protein DJ-1 plays an essential role in modulating DNA double-strand break (DSB) r...

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Detalles Bibliográficos
Autores principales:	Wang, Zhong-Xuan, Liu, Yi, Li, Yao-Lin, Wei, Qiao, Lin, Rong-Rong, Kang, Ruiqing, Ruan, Yang, Lin, Zhi-Hao, Xue, Nai-Jia, Zhang, Bao-Rong, Pu, Jia-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218208/ https://www.ncbi.nlm.nih.gov/pubmed/37239999 http://dx.doi.org/10.3390/ijms24108651

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