Cargando…

Ionic Levothyroxine Formulations: Synthesis, Bioavailability, and Cytotoxicity Studies

Thyroid diseases affect a considerable portion of the population, with hypothyroidism being one of the most commonly reported thyroid diseases. Levothyroxine (T4) is clinically used to treat hypothyroidism and suppress thyroid stimulating hormone secretion in other thyroid diseases. In this work, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barreira, António, Santos, Andreia F. M., Dionísio, Madalena, Jesus, Ana R., Duarte, Ana Rita C., Petrovski, Željko, Paninho, Ana B., Ventura, Márcia G., Branco, Luis C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218257/ https://www.ncbi.nlm.nih.gov/pubmed/37240166 http://dx.doi.org/10.3390/ijms24108822

Ejemplares similares

Organic Salts Based on Isoniazid Drug: Synthesis, Bioavailability and Cytotoxicity Studies
por: Santos, Filipa, et al.
Publicado: (2020)

Antimicrobial Activities of Highly Bioavailable Organic Salts and Ionic Liquids from Fluoroquinolones
por: Santos, Miguel M., et al.
Publicado: (2020)

Synthesis and Biological Evaluation of Amphotericin B Formulations Based on Organic Salts and Ionic Liquids against Leishmania infantum
por: Ferraz, Ricardo, et al.
Publicado: (2022)

P-glycoprotein polymorphism and levothyroxine bioavailability in hypothyroid patients
por: Öztaş, Ezgi, et al.
Publicado: (2018)

Takotsubo Cardiomyopathy Associated with Levothyroxine Over-replacement
por: Balsa, Ana Margarida, et al.
Publicado: (2017)

Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review
por: Liu, Hanqing, et al.
Publicado: (2023)

Synthesis and Antibacterial Activity of Ionic Liquids and Organic Salts Based on Penicillin G and Amoxicillin hydrolysate Derivatives against Resistant Bacteria
por: Ferraz, Ricardo, et al.
Publicado: (2020)

Levothyroxine Bioequivalence Study and Its Narrow Therapeutic Index: Comparative Bioavailability Results Between Two Formulations Available in Latin America
por: Bertoncini, Carlos Walter, et al.
Publicado: (2022)

Strategies to Overcome Heparins’ Low Oral Bioavailability
por: Neves, Ana Rita, et al.
Publicado: (2016)

Levothyroxine: Conventional and Novel Drug Delivery Formulations
por: Liu, Hanqing, et al.
Publicado: (2022)

Ionic-liquid-based approaches to improve biopharmaceuticals downstream processing and formulation
por: Almeida, Catarina, et al.
Publicado: (2023)

Levothyroxine Formulations: Pharmacological and Clinical Implications of Generic Substitution
por: Benvenga, Salvatore, et al.
Publicado: (2019)

Application of Covalent Organic Frameworks (COFs) as Dyes and Additives for Dye-Sensitized Solar Cells (DSSCs)
por: Inácio, Diogo, et al.
Publicado: (2023)

Corrigendum: Ionic-liquid-based approaches to improve biopharmaceuticals downstream processing and formulation
por: Almeida, Catarina, et al.
Publicado: (2023)

Pharmacokinetics and Comparative Bioavailability of a Levothyroxine Sodium Oral Solution and Soft Capsule
por: Tanguay, Mario, et al.
Publicado: (2018)

Enhanced In Vitro Antiviral Activity of Hydroxychloroquine Ionic Liquids against SARS-CoV-2
por: Faísca, Francisco, et al.
Publicado: (2022)

A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors
por: Orienti, Isabella, et al.
Publicado: (2019)

Pharmacokinetics of coadministration of levothyroxine sodium and alendronate sodium new effervescent formulation
por: Bone, H. G., et al.
Publicado: (2017)

Levothyroxine Tablet Malabsorption Associated with Gastroparesis Corrected with Gelatin Capsule Formulation
por: Reardon, David P., et al.
Publicado: (2016)

Different Formulations of Levothyroxine for Treating Hypothyroidism: A Real-Life Study
por: Trimboli, Pierpaolo, et al.
Publicado: (2020)

RF23 | PSAT259 Comparable Bioavailability of a Novel Levothyroxine Solution when Administered with Coffee
por: Washington, Kris, et al.
Publicado: (2022)

Tailoring amphotericin B as an ionic liquid: an upfront strategy to potentiate the biological activity of antifungal drugs
por: Hartmann, Diego O., et al.
Publicado: (2021)

Liquid levothyroxine formulations in patients taking drugs interfering with L-T4 absorption
por: Gatta, Elisa, et al.
Publicado: (2022)

Therapeutic Liquid Formulations Based on Low Transition Temperature Mixtures for the Incorporation of Anti-Inflammatory Drugs
por: Roda, Ana, et al.
Publicado: (2021)

Mood Disorders in Levothyroxine-Treated Hypothyroid Women
por: Romero-Gómez, Benjamín, et al.
Publicado: (2019)

Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism
por: Shakir, Mohamed K M, et al.
Publicado: (2021)

Comparative Bioavailability of Different Coenzyme Q10 Formulations in Healthy Elderly Individuals
por: Pravst, Igor, et al.
Publicado: (2020)

Retrospective Study of Patients Switched from Tablet Formulations to a Gel Cap Formulation of Levothyroxine: Results of the CONTROL Switch Study
por: Ernst, Frank R., et al.
Publicado: (2016)

Oral Liquid Formulation of Levothyroxine Is Stable in Breakfast Beverages and May Improve Thyroid Patient Compliance
por: Bernareggi, Alberto, et al.
Publicado: (2013)

Shift from Levothyroxine Tablets to Liquid Formulation at Breakfast  Improves Quality of Life of Hypothyroid Patients
por: Guglielmi, Rinaldo, et al.
Publicado: (2018)

Thyroid Hormone Profile in Patients Ingesting Soft Gel Capsule or Liquid Levothyroxine Formulations with Breakfast
por: Cappelli, Carlo, et al.
Publicado: (2016)

Liquid Levothyroxine Formulation Taken during Lunch in Italy: A Case Report and Review of the Literature
por: Cappelli, Carlo, et al.
Publicado: (2020)

Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione
por: Buonocore, Daniela, et al.
Publicado: (2016)

Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
por: Lin, Yiping, et al.
Publicado: (2021)

Nanotechnology-based formulations to amplify intraocular bioavailability
por: Kagkelaris, Konstantinos, et al.
Publicado: (2022)

The Neurophysiological Impact of Subacute Stroke: Changes in Cortical Oscillations Evoked by Bimanual Finger Movement
por: Dionísio, Ana, et al.
Publicado: (2022)

Levothyroxine malabsorption or pseudomalabsorption? A question in the management of refractory hypothyroidism
por: Santos Monteiro, Sílvia, et al.
Publicado: (2022)

Adequate timing and constant supervision are the keys for successful implementation of levothyroxine or levothyroxine/paracetamol absorption test
por: Lewandowski, Krzysztof C., et al.
Publicado: (2020)

Evaluation of the Cytotoxicity of Ayahuasca Beverages
por: Simão, Ana Y., et al.
Publicado: (2020)

Drug rash induced by levothyroxine and oral desensitization
por: Dortas, Sérgio Duarte, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_e7vl1soq15rkbb52eq9cmt3ibc