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No Substrate Left behind—Mining of Shotgun Proteomics Datasets Rescues Evidence of Proteolysis by SARS-CoV-2 3CL(pro) Main Protease

Proteolytic processing is the most ubiquitous post-translational modification and regulator of protein function. To identify protease substrates, and hence the function of proteases, terminomics workflows have been developed to enrich and detect proteolytically generated protein termini from mass sp...

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Detalles Bibliográficos
Autores principales:	Bell, Peter A., Overall, Christopher M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218362/ https://www.ncbi.nlm.nih.gov/pubmed/37240067 http://dx.doi.org/10.3390/ijms24108723

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