Mendelian Randomization and Transcriptome-Wide Association Analysis Identified Genes That Were Pleiotropically Associated with Intraocular Pressure

Background: Intraocular pressure (IOP) is a major modifiable risk factor for glaucoma. However, the mechanisms underlying the controlling of IOP remain to be elucidated. Objective: To prioritize genes that are pleiotropically associated with IOP. Methods: We adopted a two-sample Mendelian randomizat...

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Detalles Bibliográficos
Autores principales: Yang, Zhikun, Zhang, Zhewei, Zhu, Yining, Yuan, Guangwei, Yang, Jingyun, Yu, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218376/
https://www.ncbi.nlm.nih.gov/pubmed/37239387
http://dx.doi.org/10.3390/genes14051027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218376/
https://www.ncbi.nlm.nih.gov/pubmed/37239387
http://dx.doi.org/10.3390/genes14051027

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