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Mendelian Randomization and Transcriptome-Wide Association Analysis Identified Genes That Were Pleiotropically Associated with Intraocular Pressure
Background: Intraocular pressure (IOP) is a major modifiable risk factor for glaucoma. However, the mechanisms underlying the controlling of IOP remain to be elucidated. Objective: To prioritize genes that are pleiotropically associated with IOP. Methods: We adopted a two-sample Mendelian randomizat...
Autores principales: | Yang, Zhikun, Zhang, Zhewei, Zhu, Yining, Yuan, Guangwei, Yang, Jingyun, Yu, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218376/ https://www.ncbi.nlm.nih.gov/pubmed/37239387 http://dx.doi.org/10.3390/genes14051027 |
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