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Association between HLA Class II Alleles/Haplotypes and Genomic Ancestry in Brazilian Patients with Type 1 Diabetes: A Nationwide Exploratory Study

We aimed to identify HLA-DRB1, -DQA1, and -DQB1 alleles/haplotypes associated with European, African, or Native American genomic ancestry (GA) in admixed Brazilian patients with type 1 diabetes (T1D). This exploratory nationwide study enrolled 1599 participants. GA percentage was inferred using a pa...

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Detalles Bibliográficos
Autores principales: Gomes, Marília Brito, Rodrigues, Vandilson, Santos, Deborah Conte, Bôas, Paulo Ricardo Villas, Silva, Dayse A., de Sousa Azulay, Rossana Santiago, Dib, Sergio Atala, Pavin, Elizabeth João, Fernandes, Virgínia Oliveira, Montenegro Junior, Renan Magalhães, Felicio, João Soares, Réa, Rosangela, Negrato, Carlos Antonio, Porto, Luís Cristóvão
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218425/
https://www.ncbi.nlm.nih.gov/pubmed/37239351
http://dx.doi.org/10.3390/genes14050991