Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies

Thirteen benzylethoxyaryl ureas have been synthesized and biologically evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins to overcome resistance phenomena offered by cancer. The antiproliferative activity of these molecules on several tumor cell lines (HT-29 and A549), on the endothel...

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Detalles Bibliográficos
Autores principales: Gil-Edo, Raquel, Hernández-Ribelles, German, Royo, Santiago, Thawait, Natasha, Serrels, Alan, Carda, Miguel, Falomir, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218498/
https://www.ncbi.nlm.nih.gov/pubmed/37239929
http://dx.doi.org/10.3390/ijms24108582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218498/
https://www.ncbi.nlm.nih.gov/pubmed/37239929
http://dx.doi.org/10.3390/ijms24108582

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