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Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies
Thirteen benzylethoxyaryl ureas have been synthesized and biologically evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins to overcome resistance phenomena offered by cancer. The antiproliferative activity of these molecules on several tumor cell lines (HT-29 and A549), on the endothel...
Autores principales: | Gil-Edo, Raquel, Hernández-Ribelles, German, Royo, Santiago, Thawait, Natasha, Serrels, Alan, Carda, Miguel, Falomir, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218498/ https://www.ncbi.nlm.nih.gov/pubmed/37239929 http://dx.doi.org/10.3390/ijms24108582 |
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