Cargando…
ITGAM rs1143679 Variant in Systemic Lupus Erythematosus Is Associated with Increased Serum Calcification Propensity
Objectives: CD11B/ITGAM (Integrin Subunit α M) mediates the adhesion of monocytes, macrophages, and granulocytes and promotes the phagocytosis of complement-coated particles. Variants of the ITGAM gene are candidates for genetic susceptibility to systemic lupus erythematosus (SLE). SNP rs1143679 (R7...
Autores principales: | Halfon, Matthieu, Zhang, Li, Ehirchiou, Driss, Pandian, Vishnuprabu Durairaj, Dahdal, Suzan, Huynh-Do, Uyen, Pasch, Andreas, Ribi, Camillo, Busso, Nathalie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218643/ https://www.ncbi.nlm.nih.gov/pubmed/37239465 http://dx.doi.org/10.3390/genes14051105 |
Ejemplares similares
-
Serum calcification propensity is independently associated with disease activity in systemic lupus erythematosus
por: Dahdal, Suzan, et al.
Publicado: (2018) -
Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation
por: Avery, Justin T., et al.
Publicado: (2019) -
The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes
por: Rhodes, Benjamin, et al.
Publicado: (2012) -
Association of the CD11b rs1143679 polymorphism with systemic lupus erythematosus in the Han Chinese population
por: Li, Chunmei, et al.
Publicado: (2017) -
Worse cardiovascular and renal outcome in male SLE patients
por: Mihailovic, Jelena, et al.
Publicado: (2023)