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Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine
Fibroblast activation proteins (FAP) are overexpressed in the tumor stroma and have received attention as target molecules for radionuclide therapy. The FAP inhibitor (FAPI) is used as a probe to deliver nuclides to cancer tissues. In this study, we designed and synthesized four novel (211)At-FAPI(s...
Autores principales: | Aso, Ayaka, Nabetani, Hinako, Matsuura, Yoshifumi, Kadonaga, Yuichiro, Shirakami, Yoshifumi, Watabe, Tadashi, Yoshiya, Taku, Mochizuki, Masayoshi, Ooe, Kazuhiro, Kawakami, Atsuko, Jinno, Naoya, Toyoshima, Atsushi, Haba, Hiromitsu, Wang, Yang, Cardinale, Jens, Giesel, Frederik Lars, Shimoyama, Atsushi, Kaneda-Nakashima, Kazuko, Fukase, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218645/ https://www.ncbi.nlm.nih.gov/pubmed/37240044 http://dx.doi.org/10.3390/ijms24108701 |
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