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Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases

OBJECTIVE: Contrast-induced encephalopathy (CIE) is a rare neurological complication that can occur in the context of various endovascular procedures. Although many potential risk factors for CIE have been reported, it is still unclear whether anesthesia is a risk factor for the occurrence of CIE. T...

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Autores principales: Zhong, Zhihong, Ni, Hongyang, Zhu, Jun, Jiang, Hong, Hu, Jinqing, Lin, Dong, Bian, Liuguan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218683/
https://www.ncbi.nlm.nih.gov/pubmed/37251226
http://dx.doi.org/10.3389/fneur.2023.1146194
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author Zhong, Zhihong
Ni, Hongyang
Zhu, Jun
Jiang, Hong
Hu, Jinqing
Lin, Dong
Bian, Liuguan
author_facet Zhong, Zhihong
Ni, Hongyang
Zhu, Jun
Jiang, Hong
Hu, Jinqing
Lin, Dong
Bian, Liuguan
author_sort Zhong, Zhihong
collection PubMed
description OBJECTIVE: Contrast-induced encephalopathy (CIE) is a rare neurological complication that can occur in the context of various endovascular procedures. Although many potential risk factors for CIE have been reported, it is still unclear whether anesthesia is a risk factor for the occurrence of CIE. The goal of this study was to investigate the incidence of CIE in patients who underwent endovascular treatment under different anesthesia methods and anesthetics administration and to explore whether general anesthesia was a potential risk factor for CIE. METHODS: We retrospectively reviewed available clinical data from 1,043 patients with neurovascular diseases undergoing endovascular treatment between June 2018 and June 2021 in our hospital. A propensity score-based matching strategy and logistic regression were used to analyze the association between anesthesia and the occurrence of CIE. RESULTS: In this study, we implemented the embolization of intracranial aneurysm in 412 patients, stent implantation of extracranial artery stenosis in 346, stent implantation of intracranial artery stenosis in 187, embolization of cerebral arteriovenous malformation or dural arteriovenous fistula in 54, endovascular thrombectomy in 20, and other endovascular treatments in 24. A total of 370 patients (35.5%) received treatment under local anesthesia, while the remaining 673 (64.5%) underwent treatment under general anesthesia. In total, 14 patients were identified as CIE, resulting in a total incidence rate of 1.34%. After propensity score-based matching of anesthesia methods, the occurrence of CIE was significantly different between the general anesthesia and local anesthesia group (P = 0.007). After propensity score-based matching of CIE, the anesthesia methods were significantly different between the two groups. Pearson contingency coefficients and logistic regression showed a significant correlation between general anesthesia and the risk of CIE. CONCLUSION: General anesthesia might be a risk factor for CIE, and propofol might be associated with the increased occurrence of CIE.
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spelling pubmed-102186832023-05-27 Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases Zhong, Zhihong Ni, Hongyang Zhu, Jun Jiang, Hong Hu, Jinqing Lin, Dong Bian, Liuguan Front Neurol Neurology OBJECTIVE: Contrast-induced encephalopathy (CIE) is a rare neurological complication that can occur in the context of various endovascular procedures. Although many potential risk factors for CIE have been reported, it is still unclear whether anesthesia is a risk factor for the occurrence of CIE. The goal of this study was to investigate the incidence of CIE in patients who underwent endovascular treatment under different anesthesia methods and anesthetics administration and to explore whether general anesthesia was a potential risk factor for CIE. METHODS: We retrospectively reviewed available clinical data from 1,043 patients with neurovascular diseases undergoing endovascular treatment between June 2018 and June 2021 in our hospital. A propensity score-based matching strategy and logistic regression were used to analyze the association between anesthesia and the occurrence of CIE. RESULTS: In this study, we implemented the embolization of intracranial aneurysm in 412 patients, stent implantation of extracranial artery stenosis in 346, stent implantation of intracranial artery stenosis in 187, embolization of cerebral arteriovenous malformation or dural arteriovenous fistula in 54, endovascular thrombectomy in 20, and other endovascular treatments in 24. A total of 370 patients (35.5%) received treatment under local anesthesia, while the remaining 673 (64.5%) underwent treatment under general anesthesia. In total, 14 patients were identified as CIE, resulting in a total incidence rate of 1.34%. After propensity score-based matching of anesthesia methods, the occurrence of CIE was significantly different between the general anesthesia and local anesthesia group (P = 0.007). After propensity score-based matching of CIE, the anesthesia methods were significantly different between the two groups. Pearson contingency coefficients and logistic regression showed a significant correlation between general anesthesia and the risk of CIE. CONCLUSION: General anesthesia might be a risk factor for CIE, and propofol might be associated with the increased occurrence of CIE. Frontiers Media S.A. 2023-05-12 /pmc/articles/PMC10218683/ /pubmed/37251226 http://dx.doi.org/10.3389/fneur.2023.1146194 Text en Copyright © 2023 Zhong, Ni, Zhu, Jiang, Hu, Lin and Bian. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Zhong, Zhihong
Ni, Hongyang
Zhu, Jun
Jiang, Hong
Hu, Jinqing
Lin, Dong
Bian, Liuguan
Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
title Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
title_full Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
title_fullStr Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
title_full_unstemmed Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
title_short Association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
title_sort association between general anesthesia and contrast-induced encephalopathy after endovascular treatment on neurovascular diseases
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218683/
https://www.ncbi.nlm.nih.gov/pubmed/37251226
http://dx.doi.org/10.3389/fneur.2023.1146194
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