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Bioinformatics Identification of Regulatory Genes and Mechanism Related to Hypoxia-Induced PD-L1 Inhibitor Resistance in Hepatocellular Carcinoma

The combination of a PD-L1 inhibitor and an anti-angiogenic agent has become the new reference standard in the first-line treatment of non-excisable hepatocellular carcinoma (HCC) due to the survival advantage, but its objective response rate remains low at 36%. Evidence shows that PD-L1 inhibitor r...

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Detalles Bibliográficos
Autores principales: Huang, Mohan, Yang, Sijun, Tai, William Chi Shing, Zhang, Lingfeng, Zhou, Yinuo, Cho, William Chi Shing, Chan, Lawrence Wing Chi, Wong, Sze Chuen Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218698/
https://www.ncbi.nlm.nih.gov/pubmed/37240068
http://dx.doi.org/10.3390/ijms24108720