Cargando…

Bioinformatics Identification of Regulatory Genes and Mechanism Related to Hypoxia-Induced PD-L1 Inhibitor Resistance in Hepatocellular Carcinoma

The combination of a PD-L1 inhibitor and an anti-angiogenic agent has become the new reference standard in the first-line treatment of non-excisable hepatocellular carcinoma (HCC) due to the survival advantage, but its objective response rate remains low at 36%. Evidence shows that PD-L1 inhibitor r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Mohan, Yang, Sijun, Tai, William Chi Shing, Zhang, Lingfeng, Zhou, Yinuo, Cho, William Chi Shing, Chan, Lawrence Wing Chi, Wong, Sze Chuen Cesar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218698/ https://www.ncbi.nlm.nih.gov/pubmed/37240068 http://dx.doi.org/10.3390/ijms24108720

Ejemplares similares

The Effect of Centrifugal Force in Quantification of Colorectal Cancer-Related mRNA in Plasma Using Targeted Sequencing
por: Xue, Vivian Weiwen, et al.
Publicado: (2018)

Augmented Features Synergize Radiomics in Post-Operative Survival Prediction and Adjuvant Therapy Recommendation for Non-Small Cell Lung Cancer
por: Chan, Lawrence Wing-Chi, et al.
Publicado: (2022)

Centipeda minima Extract Attenuates Dextran Sodium Sulfate-Induced Acute Colitis in Mice by Inhibiting Macrophage Activation and Monocyte Chemotaxis
por: Chan, Brandon Dow, et al.
Publicado: (2021)

Cell-free circulating tumor RNAs in plasma as the potential prognostic biomarkers in colorectal cancer
por: Jin, Nana, et al.
Publicado: (2023)

Primary Tumor Radiomic Model for Identifying Extrahepatic Metastasis of Hepatocellular Carcinoma Based on Contrast Enhanced Computed Tomography
por: Chan, Lawrence Wing Chi, et al.
Publicado: (2022)

Nasopharyngeal carcinoma: molecular biomarker discovery and progress
por: Cho, William Chi-shing
Publicado: (2007)

Research progress in SELDI-TOF MS and its clinical applications
por: CHO, William Chi-Shing
Publicado: (2006)

Exploring the Role of Circulating Cell-Free RNA in the Development of Colorectal Cancer
por: Kan, Chau-Ming, et al.
Publicado: (2023)

Combination therapy of gefitinib and miR-30a-5p may overcome acquired drug resistance through regulating the PI3K/AKT pathway in non-small cell lung cancer
por: Wang, Fengfeng, et al.
Publicado: (2020)

Lessons Learnt from Evidence-Based Approach of Using Chinese Herbal Medicines in Liver Cancer
por: Zheng, Zhan, et al.
Publicado: (2013)

Scalable synthesis enabling multilevel bio-evaluations of natural products for discovery of lead compounds
por: Zhu, Lizhi, et al.
Publicado: (2018)

MiR-30 Family Potentially Targeting PI3K-SIAH2 Predicted Interaction Network Represents a Novel Putative Theranostic Panel in Non-small Cell Lung Cancer
por: Chan, Lawrence W. C., et al.
Publicado: (2017)

Prediction of Chinese Reading Fluency by Verbal and Non-verbal Visual Attention Span Measures
por: Chan, Kevin Shing-Chi, et al.
Publicado: (2020)

Synthesis and Evaluation of Novel Anticancer Compounds Derived from the Natural Product Brevilin A
por: Lee, Magnolia Muk-Lan, et al.
Publicado: (2020)

The clinical characteristics of pediatric patients infected by SARS-CoV-2 Omicron variant and whole viral genome sequencing analysis
por: Tsang, Hin Fung, et al.
Publicado: (2023)

Brevilin A Induces Cell Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma
por: Liu, Rui, et al.
Publicado: (2019)

Targeted Sequencing Approach and Its Clinical Applications for the Molecular Diagnosis of Human Diseases
por: Pei, Xiao Meng, et al.
Publicado: (2023)

MiR-1180 promotes apoptotic resistance to human hepatocellular carcinoma via activation of NF-κB signaling pathway
por: Tan, Guosheng, et al.
Publicado: (2016)

Identification of Novel SCN5A Single Nucleotide Variants in Brugada Syndrome: A Territory-Wide Study From Hong Kong
por: Tse, Gary, et al.
Publicado: (2020)

Gynostemma pentaphyllum saponins attenuate inflammation in vitro and in vivo by inhibition of NF-κB and STAT3 signaling
por: Wong, Wing-Yan, et al.
Publicado: (2017)

Rhynchophylline Protects Cultured Rat Neurons against Methamphetamine Cytotoxicity
por: Xu, Dan Dan, et al.
Publicado: (2012)

Medicinal Plants in the Prevention and Treatment of Chronic Diseases 2013
por: Eddouks, Mohamed, et al.
Publicado: (2014)

Editorial: Epitranscriptomics: The Novel RNA Frontier
por: Nigita, Giovanni, et al.
Publicado: (2018)

Correction to: CRISPR-Cas, a robust gene-editing technology in the era of modern cancer immunotherapy
por: Miri, Seyed Mohammad, et al.
Publicado: (2020)

CRISPR-Cas, a robust gene-editing technology in the era of modern cancer immunotherapy
por: Miri, Seyed Mohammad, et al.
Publicado: (2020)

Cost-effectiveness of Pembrolizumab as a Second-Line Therapy for Hepatocellular Carcinoma
por: Chiang, Chi-leung, et al.
Publicado: (2021)

Lactobacillus casei Strain Shirota Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Increasing Taurine-Conjugated Bile Acids and Inhibiting NF-κB Signaling via Stabilization of IκBα
por: Wong, Wing-Yan, et al.
Publicado: (2022)

Arnicolide D, from the herb Centipeda minima, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma
por: Liu, Rui, et al.
Publicado: (2019)

Propofol total intravenous anaesthesia versus inhalational anaesthesia for acute postoperative pain in patients with morphine patient-controlled analgesia: a large-scale retrospective study with covariate adjustment
por: Wong, Stanley Sau Ching, et al.
Publicado: (2022)

Mitochondria Homeostasis and Oxidant/Antioxidant Balance in Skeletal Muscle—Do Myokines Play a Role?
por: Pang, Brian Pak Shing, et al.
Publicado: (2021)

Can the Testing Effect for General Knowledge Facts Be Influenced by Distraction due to Divided Attention or Experimentally Induced Anxious Mood?
por: Tse, Chi-Shing, et al.
Publicado: (2019)

First-Line Atezolizumab Plus Bevacizumab versus Sorafenib in Hepatocellular Carcinoma: A Cost-Effectiveness Analysis
por: Chiang, Chi-Leung, et al.
Publicado: (2021)

URG4/URGCP enhances the angiogenic capacity of human hepatocellular carcinoma cells in vitro via activation of the NF-κB signaling pathway
por: Xing, Sizhong, et al.
Publicado: (2015)

Long Non-Coding RNAs in Multidrug Resistance of Glioblastoma
por: Mahinfar, Parvaneh, et al.
Publicado: (2021)

Anti-cancer Activity of Centipeda minima Extract in Triple Negative Breast Cancer via Inhibition of AKT, NF-κB, and STAT3 Signaling Pathways
por: Lee, Magnolia Muk-Lan, et al.
Publicado: (2020)

Arnicolide D Inhibits Triple Negative Breast Cancer Cell Proliferation by Suppression of Akt/mTOR and STAT3 Signaling Pathways
por: Qu, Zhao, et al.
Publicado: (2020)

Brevilin A, a Natural Sesquiterpene Lactone Inhibited the Growth of Triple-Negative Breast Cancer Cells via Akt/mTOR and STAT3 Signaling Pathways
por: Qu, Zhao, et al.
Publicado: (2020)

Combined Stereotactic Body Radiotherapy and Immunotherapy Versus Transarterial Chemoembolization in Locally Advanced Hepatocellular Carcinoma: A Propensity Score Matching Analysis
por: Chiang, Chi-Leung, et al.
Publicado: (2021)

Scientific Basis of Mind-Body Interventions
por: Tsang, Hector, et al.
Publicado: (2014)

The relationship between language proficiency and attentional control in Cantonese-English bilingual children: evidence from Simon, Simon switching, and working memory tasks
por: Tse, Chi-Shing, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qc8bunaefu4k8quongprclpjhl