Cargando…
Investigating Mammalian Formins with SMIFH2 Fifteen Years in: Novel Targets and Unexpected Biology
The mammalian formin family comprises fifteen multi-domain proteins that regulate actin dynamics and microtubules in vitro and in cells. Evolutionarily conserved formin homology (FH) 1 and 2 domains allow formins to locally modulate the cell cytoskeleton. Formins are involved in several developmenta...
Autor principal: | Innocenti, Metello |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218792/ https://www.ncbi.nlm.nih.gov/pubmed/37240404 http://dx.doi.org/10.3390/ijms24109058 |
Ejemplares similares
-
SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton
por: Isogai, Tadamoto, et al.
Publicado: (2015) -
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily
por: Nishimura, Yukako, et al.
Publicado: (2021) -
Alterations to the broad-spectrum formin inhibitor SMIFH2 modulate potency but not specificity
por: Orman, Marina, et al.
Publicado: (2022) -
SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics
por: Green, Hannah L. H., et al.
Publicado: (2020) -
Abnormal left-right organizer and laterality defects in Xenopus embryos after formin inhibitor SMIFH2 treatment
por: Petri, Natalia, et al.
Publicado: (2022)