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PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent

Alzheimer’s disease (AD) is a chronic neurological condition characterized by the severe loss of cholinergic neurons. Currently, the incomplete understanding of the loss of neurons has prevented curative treatments for familial AD (FAD). Therefore, modeling FAD in vitro is essential for studying cho...

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Detalles Bibliográficos
Autores principales:	Mendivil-Perez, Miguel, Velez-Pardo, Carlos, Lopera, Francisco, Kosik, Kenneth S., Jimenez-Del-Rio, Marlene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218810/ https://www.ncbi.nlm.nih.gov/pubmed/37240306 http://dx.doi.org/10.3390/ijms24108957

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