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Are Genetic Modifiers the Answer to Different Responses to Hydroxyurea Treatment?—A Pharmacogenetic Study in Sickle Cell Anemia Angolan Children

Sickle cell anemia (SCA) is an inherited disease affecting the hemoglobin that is particularly common in sub-Saharan Africa. Although monogenic, phenotypes are markedly heterogeneous in terms of severity and life span. Hydroxyurea is still the most common treatment for these patients, and the respon...

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Detalles Bibliográficos
Autores principales:	Ginete, Catarina, Delgadinho, Mariana, Santos, Brígida, Pinto, Vera, Silva, Carina, Miranda, Armandina, Brito, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218819/ https://www.ncbi.nlm.nih.gov/pubmed/37240136 http://dx.doi.org/10.3390/ijms24108792

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