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One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population

Background: The aim of our study was to provide real-world data on outcomes for elderly Taiwanese patients who underwent transcatheter aortic valve replacement or surgical aortic valve replacement in different risk groups. Methods: From March 2011 through December 2021, 177 patients with severe aort...

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Autores principales: Lin, Po-Han, Wei, Hao-Ji, Hsieh, Shih-Rong, Tsai, Hung-Wen, Yu, Chu-Leng, Lee, Wen-Lieng, Wu, Yung-Szu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219031/
https://www.ncbi.nlm.nih.gov/pubmed/37240534
http://dx.doi.org/10.3390/jcm12103429
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author Lin, Po-Han
Wei, Hao-Ji
Hsieh, Shih-Rong
Tsai, Hung-Wen
Yu, Chu-Leng
Lee, Wen-Lieng
Wu, Yung-Szu
author_facet Lin, Po-Han
Wei, Hao-Ji
Hsieh, Shih-Rong
Tsai, Hung-Wen
Yu, Chu-Leng
Lee, Wen-Lieng
Wu, Yung-Szu
author_sort Lin, Po-Han
collection PubMed
description Background: The aim of our study was to provide real-world data on outcomes for elderly Taiwanese patients who underwent transcatheter aortic valve replacement or surgical aortic valve replacement in different risk groups. Methods: From March 2011 through December 2021, 177 patients with severe aortic stenosis who were ≥70 years old and had undergone TAVI (transcatheter aortic valve implantation) or SAVR (surgical aortic valve replacement) in a single center were divided by STS score (<4%, 4–8% and >8%) into three different groups. Then, we compared their clinical characteristics, operative complications, and all-cause mortality. Results: In all risk groups, there were no significant differences in in-hospital mortality, or 1-year and 5-year mortality between patients in the TAVI and SAVR groups. In all risk groups, patients in the TAVI group had shorter hospital stay and higher rate of paravalvular leakage than the SAVR group. After univariate analysis, BMI (body mass index) < 20 was a risk factor for higher 1-year and 5-year mortality. In the multivariate analysis, acute kidney injury was an independent factor for predicting worse outcomes in terms of 1-year and 5-year mortality. Conclusions: Taiwan elderly patients in all risk groups did not have significant differences in mortality rates between the TAVI and the SAVR group. However, the TAVI group had shorter hospital stay and higher rate of paravalvular leakage in all risk groups.
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spelling pubmed-102190312023-05-27 One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population Lin, Po-Han Wei, Hao-Ji Hsieh, Shih-Rong Tsai, Hung-Wen Yu, Chu-Leng Lee, Wen-Lieng Wu, Yung-Szu J Clin Med Article Background: The aim of our study was to provide real-world data on outcomes for elderly Taiwanese patients who underwent transcatheter aortic valve replacement or surgical aortic valve replacement in different risk groups. Methods: From March 2011 through December 2021, 177 patients with severe aortic stenosis who were ≥70 years old and had undergone TAVI (transcatheter aortic valve implantation) or SAVR (surgical aortic valve replacement) in a single center were divided by STS score (<4%, 4–8% and >8%) into three different groups. Then, we compared their clinical characteristics, operative complications, and all-cause mortality. Results: In all risk groups, there were no significant differences in in-hospital mortality, or 1-year and 5-year mortality between patients in the TAVI and SAVR groups. In all risk groups, patients in the TAVI group had shorter hospital stay and higher rate of paravalvular leakage than the SAVR group. After univariate analysis, BMI (body mass index) < 20 was a risk factor for higher 1-year and 5-year mortality. In the multivariate analysis, acute kidney injury was an independent factor for predicting worse outcomes in terms of 1-year and 5-year mortality. Conclusions: Taiwan elderly patients in all risk groups did not have significant differences in mortality rates between the TAVI and the SAVR group. However, the TAVI group had shorter hospital stay and higher rate of paravalvular leakage in all risk groups. MDPI 2023-05-12 /pmc/articles/PMC10219031/ /pubmed/37240534 http://dx.doi.org/10.3390/jcm12103429 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Po-Han
Wei, Hao-Ji
Hsieh, Shih-Rong
Tsai, Hung-Wen
Yu, Chu-Leng
Lee, Wen-Lieng
Wu, Yung-Szu
One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population
title One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population
title_full One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population
title_fullStr One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population
title_full_unstemmed One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population
title_short One-Year and Five-Year Outcomes of Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Taiwanese Elderly Population
title_sort one-year and five-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement in a taiwanese elderly population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219031/
https://www.ncbi.nlm.nih.gov/pubmed/37240534
http://dx.doi.org/10.3390/jcm12103429
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