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A Dominant-Negative Mutant of ANXA7 Impairs Calcium Signaling and Enhances the Proliferation of Prostate Cancer Cells by Downregulating the IP3 Receptor and the PI3K/mTOR Pathway

Annexin A7/ANXA7 is a calcium-dependent membrane fusion protein with tumor suppressor gene (TSG) properties, which is located on chromosome 10q21 and is thought to function in the regulation of calcium homeostasis and tumorigenesis. However, whether the molecular mechanisms for tumor suppression are...

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Detalles Bibliográficos
Autores principales: Srivastava, Meera, Bera, Alakesh, Eidelman, Ofer, Tran, Minh B., Jozwik, Catherine, Glasman, Mirta, Leighton, Ximena, Caohuy, Hung, Pollard, Harvey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219041/
https://www.ncbi.nlm.nih.gov/pubmed/37240163
http://dx.doi.org/10.3390/ijms24108818