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Structural Insights into Phosphorylation-Mediated Polymerase Function Loss for DNA Polymerase β Bound to Gapped DNA

DNA polymerase [Formula: see text] is a member of the X-family of DNA polymerases, playing a critical role in the base excision repair (BER) pathway in mammalian cells by implementing the nucleotide gap-filling step. In vitro phosphorylation of DNA polymerase [Formula: see text] with PKC on S44 caus...

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Detalles Bibliográficos
Autores principales:	Srivastava, Amit, Idriss, Haitham, Homouz, Dirar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219072/ https://www.ncbi.nlm.nih.gov/pubmed/37240334 http://dx.doi.org/10.3390/ijms24108988

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