Cargando…

Oligomeric Alpha-Synuclein and STX-1A from Neural-Derived Extracellular Vesicles (NDEVs) as Possible Biomarkers of REM Sleep Behavior Disorder in Parkinson’s Disease: A Preliminary Cohort Study

REM sleep behavior disorder (RBD) has a tighter link with synucleinopathies than other neurodegenerative disorders. Parkinson’s Disease (PD) patients with RBD have a more severe motor and cognitive impairment; biomarkers for RBD are currently unavailable. Synaptic accumulation of α-Syn oligomers and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meloni, Mario, Agliardi, Cristina, Guerini, Franca Rosa, Saibene, Francesca Lea, Milner, Anna Vera, Zanzottera, Milena, Bolognesi, Elisabetta, Puligheddu, Monica, Figorilli, Michela, Navarro, Jorge, Clerici, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219080/ https://www.ncbi.nlm.nih.gov/pubmed/37240185 http://dx.doi.org/10.3390/ijms24108839

Ejemplares similares

Considering REM Sleep Behavior Disorder in the Management of Parkinson’s Disease
por: Figorilli, Michela, et al.
Publicado: (2023)

VDR Gene Single Nucleotide Polymorphisms and Autoimmunity: A Narrative Review
por: Agliardi, Cristina, et al.
Publicado: (2023)

Alpha-synuclein as a biomarker in Parkinson's disease: focus on neural derived extracelluar vesicles
por: Agliardi, Cristina, et al.
Publicado: (2021)

The Syntaxin-1A gene single nucleotide polymorphism rs4717806 associates with the risk of ischemic heart disease
por: Guerini, Franca R., et al.
Publicado: (2019)

Two Single Nucleotide Polymorphisms in the Purinergic Receptor P2X7 Gene Are Associated with Disease Severity in Multiple Sclerosis
por: Guerini, Franca Rosa, et al.
Publicado: (2022)

Vitamin D Receptor Gene Polymorphism Predicts the Outcome of Multidisciplinary Rehabilitation in Multiple Sclerosis Patients
por: Guerini, Franca Rosa, et al.
Publicado: (2023)

Myelin Basic Protein in Oligodendrocyte-Derived Extracellular Vesicles as a Diagnostic and Prognostic Biomarker in Multiple Sclerosis: A Pilot Study
por: Agliardi, Cristina, et al.
Publicado: (2023)

GC1f Vitamin D Binding Protein Isoform as a Marker of Severity in Autism Spectrum Disorders
por: Bolognesi, Elisabetta, et al.
Publicado: (2022)

The Role of SNAP-25 in Autism Spectrum Disorders Onset Patterns
por: Bolognesi, Elisabetta, et al.
Publicado: (2023)

Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease
por: Meloni, Mario, et al.
Publicado: (2021)

Alterations of natural killer cells activatory molecules phenotype and function in mothers of ASD children: a pilot study
por: Saresella, Marina, et al.
Publicado: (2023)

Vestibular Evoked Myogenic Potentials Are Abnormal in Idiopathic REM Sleep Behavior Disorder
por: de Natale, Edoardo Rosario, et al.
Publicado: (2018)

HLA Allele Frequencies and Association with Severity of COVID-19 Infection in Northern Italian Patients
por: Guerini, Franca Rosa, et al.
Publicado: (2022)

Activating KIR/HLA complexes in classic Kaposi's Sarcoma
por: Guerini, Franca R, et al.
Publicado: (2012)

The Isoform GC1f of the Vitamin D Binding Protein Is Associated with Bronchiectasis Severity
por: Oriano, Martina, et al.
Publicado: (2021)

Neurophysiological Aspects of REM Sleep Behavior Disorder (RBD): A Narrative Review
por: Figorilli, Michela, et al.
Publicado: (2021)

HLA alleles modulate EBV viral load in multiple sclerosis
por: Agostini, Simone, et al.
Publicado: (2018)

SNAP-25 Single Nucleotide Polymorphisms, Brain Morphology and Intelligence in Children With Borderline Intellectual Functioning: A Mediation Analysis
por: Blasi, Valeria, et al.
Publicado: (2021)

Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients
por: Al-Daghri, Nasser M., et al.
Publicado: (2016)

Reduced Intracortical Facilitation to TMS in Both Isolated REM Sleep Behavior Disorder (RBD) and Early Parkinson’s Disease with RBD
por: Lanza, Giuseppe, et al.
Publicado: (2022)

Predictive risk factors of phenoconversion in idiopathic REM sleep behavior disorder: the Italian study “FARPRESTO”
por: Puligheddu, Monica, et al.
Publicado: (2022)

Correction to: Predictive risk factors of phenoconversion in idiopathic REM sleep behavior disorder: the Italian study “FARPRESTO”
por: Puligheddu, Monica, et al.
Publicado: (2022)

NK Cell Subpopulations and Receptor Expression in Recovering SARS-CoV-2 Infection
por: Saresella, Marina, et al.
Publicado: (2021)

Relationship between herpes simplex virus-1-specific antibody titers and cortical brain damage in Alzheimer’s disease and amnestic mild cognitive impairment
por: Mancuso, Roberta, et al.
Publicado: (2014)

Blood extracellular vesicles (EVs) of central nervous system origin: a window into the brain
por: Agliardi, Cristina, et al.
Publicado: (2019)

A role for activatory KIR/HLA complexes in HIV-associated Kaposi’s sarcoma development
por: Agostini, Simone, et al.
Publicado: (2011)

miR-23a-3p and miR-181a-5p modulate SNAP-25 expression
por: Agostini, Simone, et al.
Publicado: (2023)

Circulatory miR-223-3p Discriminates Between Parkinson’s and Alzheimer’s Patients
por: Mancuso, Roberta, et al.
Publicado: (2019)

Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson’s Disease
por: Vivacqua, Giorgio, et al.
Publicado: (2016)

A Possible Role for HSV-1-Specific Humoral Response and PILRA rs1859788 Polymorphism in the Pathogenesis of Parkinson’s Disease
por: Agostini, Simone, et al.
Publicado: (2021)

Inflammatory Responses to Monomeric and Aggregated α-Synuclein in Peripheral Blood of Parkinson Disease Patients
por: Piancone, Federica, et al.
Publicado: (2021)

Mechanisms that Determine the Differential Stability of Stx(+) and Stx(−) Lysogens
por: Colon, Michael P., et al.
Publicado: (2016)

Drug Targeting of α-Synuclein Oligomerization in Synucleinopathies
por: Outeiro, Tiago Fleming, et al.
Publicado: (2008)

Microtubule Depolymerization Potentiates Alpha-Synuclein Oligomerization
por: Esteves, A. Raquel, et al.
Publicado: (2010)

Gender and Nightshift Work: A Cross Sectional Study on Sleep Quality and Daytime Somnolence
por: Lecca, Rosamaria, et al.
Publicado: (2023)

Prevalence of sleep disruption and determinants of sleepiness in a cohort of Italian hospital physicians: The PRESOMO study
por: Lecca, Rosamaria, et al.
Publicado: (2021)

Sleep‐related hypermotor epilepsy and non‐rapid eye movement parasomnias: Differences in the periodic and aperiodic component of the electroencephalographic power spectra
por: Pani, Sara M., et al.
Publicado: (2021)

Acetylated α-Tubulin and α-Synuclein: Physiological Interplay and Contribution to α-Synuclein Oligomerization
por: Calogero, Alessandra Maria, et al.
Publicado: (2023)

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD
por: Esteves, A. R., et al.
Publicado: (2011)

Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism
por: van Rooijen, Bart D., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_1h9b03m1ic8kcr94i55etvgu0l