Management of the Sickle Cell Trait: An Opinion by Expert Panel Members

The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carri...

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Detalles Bibliográficos
Autores principales: Pinto, Valeria Maria, De Franceschi, Lucia, Gianesin, Barbara, Gigante, Antonia, Graziadei, Giovanna, Lombardini, Letizia, Palazzi, Giovanni, Quota, Alessandra, Russo, Rodolfo, Sainati, Laura, Venturelli, Donatella, Forni, Gian Luca, Origa, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219090/
https://www.ncbi.nlm.nih.gov/pubmed/37240547
http://dx.doi.org/10.3390/jcm12103441
Descripción
Sumario:The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carrier states, Sickle Cell Trait (SCT) seems to be a risk factor for several clinical complications, such as extreme exertional injury, chronic kidney disease, and complications during pregnancy and surgery. This expert panel believes that increasing knowledge about these clinical manifestations and their prevention and management can be a useful tool for all healthcare providers involved in this issue.

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