Management of the Sickle Cell Trait: An Opinion by Expert Panel Members

The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carri...

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Autores principales: Pinto, Valeria Maria, De Franceschi, Lucia, Gianesin, Barbara, Gigante, Antonia, Graziadei, Giovanna, Lombardini, Letizia, Palazzi, Giovanni, Quota, Alessandra, Russo, Rodolfo, Sainati, Laura, Venturelli, Donatella, Forni, Gian Luca, Origa, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219090/
https://www.ncbi.nlm.nih.gov/pubmed/37240547
http://dx.doi.org/10.3390/jcm12103441
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author Pinto, Valeria Maria
De Franceschi, Lucia
Gianesin, Barbara
Gigante, Antonia
Graziadei, Giovanna
Lombardini, Letizia
Palazzi, Giovanni
Quota, Alessandra
Russo, Rodolfo
Sainati, Laura
Venturelli, Donatella
Forni, Gian Luca
Origa, Raffaella
author_facet Pinto, Valeria Maria
De Franceschi, Lucia
Gianesin, Barbara
Gigante, Antonia
Graziadei, Giovanna
Lombardini, Letizia
Palazzi, Giovanni
Quota, Alessandra
Russo, Rodolfo
Sainati, Laura
Venturelli, Donatella
Forni, Gian Luca
Origa, Raffaella
author_sort Pinto, Valeria Maria
collection PubMed
description The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carrier states, Sickle Cell Trait (SCT) seems to be a risk factor for several clinical complications, such as extreme exertional injury, chronic kidney disease, and complications during pregnancy and surgery. This expert panel believes that increasing knowledge about these clinical manifestations and their prevention and management can be a useful tool for all healthcare providers involved in this issue.
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spelling pubmed-102190902023-05-27 Management of the Sickle Cell Trait: An Opinion by Expert Panel Members Pinto, Valeria Maria De Franceschi, Lucia Gianesin, Barbara Gigante, Antonia Graziadei, Giovanna Lombardini, Letizia Palazzi, Giovanni Quota, Alessandra Russo, Rodolfo Sainati, Laura Venturelli, Donatella Forni, Gian Luca Origa, Raffaella J Clin Med Review The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carrier states, Sickle Cell Trait (SCT) seems to be a risk factor for several clinical complications, such as extreme exertional injury, chronic kidney disease, and complications during pregnancy and surgery. This expert panel believes that increasing knowledge about these clinical manifestations and their prevention and management can be a useful tool for all healthcare providers involved in this issue. MDPI 2023-05-12 /pmc/articles/PMC10219090/ /pubmed/37240547 http://dx.doi.org/10.3390/jcm12103441 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pinto, Valeria Maria
De Franceschi, Lucia
Gianesin, Barbara
Gigante, Antonia
Graziadei, Giovanna
Lombardini, Letizia
Palazzi, Giovanni
Quota, Alessandra
Russo, Rodolfo
Sainati, Laura
Venturelli, Donatella
Forni, Gian Luca
Origa, Raffaella
Management of the Sickle Cell Trait: An Opinion by Expert Panel Members
title Management of the Sickle Cell Trait: An Opinion by Expert Panel Members
title_full Management of the Sickle Cell Trait: An Opinion by Expert Panel Members
title_fullStr Management of the Sickle Cell Trait: An Opinion by Expert Panel Members
title_full_unstemmed Management of the Sickle Cell Trait: An Opinion by Expert Panel Members
title_short Management of the Sickle Cell Trait: An Opinion by Expert Panel Members
title_sort management of the sickle cell trait: an opinion by expert panel members
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219090/
https://www.ncbi.nlm.nih.gov/pubmed/37240547
http://dx.doi.org/10.3390/jcm12103441
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