A New Opportunity for “Old” Molecules: Targeting PARP1 Activity through a Non-Enzymatic Mechanism

In recent years, new therapies have been developed based on molecules that target molecular mechanisms involved in both the initiation and maintenance of the oncogenic process. Among these molecules are the poly(ADP-ribose) polymerase 1 (PARP1) inhibitors. PARP1 has emerged as a target with great th...

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Detalles Bibliográficos
Autores principales: Iglesias, Pablo, Seoane, Marcos, Golán-Cancela, Irene, Fraga, Máximo, Arce, Victor M., Costoya, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219095/
https://www.ncbi.nlm.nih.gov/pubmed/37240195
http://dx.doi.org/10.3390/ijms24108849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219095/
https://www.ncbi.nlm.nih.gov/pubmed/37240195
http://dx.doi.org/10.3390/ijms24108849

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