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A New Opportunity for “Old” Molecules: Targeting PARP1 Activity through a Non-Enzymatic Mechanism
In recent years, new therapies have been developed based on molecules that target molecular mechanisms involved in both the initiation and maintenance of the oncogenic process. Among these molecules are the poly(ADP-ribose) polymerase 1 (PARP1) inhibitors. PARP1 has emerged as a target with great th...
Autores principales: | Iglesias, Pablo, Seoane, Marcos, Golán-Cancela, Irene, Fraga, Máximo, Arce, Victor M., Costoya, Jose A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219095/ https://www.ncbi.nlm.nih.gov/pubmed/37240195 http://dx.doi.org/10.3390/ijms24108849 |
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