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Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study

This study aimed to address the stability of orthodontic mini-implants submitted to an immediate orthodontic functional load, in splinted or unsplinted conditions, further characterizing the histomorphometric parameters of the neighboring bone tissue, in an in vivo experimental model. Mini-implants...

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Autores principales: Fontes, Joana, Martin, Victor Zacharias, Resende, Marta, Colaço, Bruno, Gomes, Pedro de Sousa, Amarante, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219099/
https://www.ncbi.nlm.nih.gov/pubmed/37233349
http://dx.doi.org/10.3390/jfb14050239
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author Fontes, Joana
Martin, Victor Zacharias
Resende, Marta
Colaço, Bruno
Gomes, Pedro de Sousa
Amarante, José Manuel
author_facet Fontes, Joana
Martin, Victor Zacharias
Resende, Marta
Colaço, Bruno
Gomes, Pedro de Sousa
Amarante, José Manuel
author_sort Fontes, Joana
collection PubMed
description This study aimed to address the stability of orthodontic mini-implants submitted to an immediate orthodontic functional load, in splinted or unsplinted conditions, further characterizing the histomorphometric parameters of the neighboring bone tissue, in an in vivo experimental model. Mini-implants (1.4 × 6.0 mm) were placed in the proximal tibia of New Zealand White rabbits and immediately loaded with a 150 g force. Tissue healing was characterized within 8 weeks. Microtomography was used to assess the mini-implants’ tipping and bone histomorphometric indexes. Loaded implants were evaluated in splinted and unsplinted conditions, with data being compared to that of unloaded mini-implants with the Kruskal–Wallis nonparametric test, followed by Dunn’s multiple comparison tests. The splinting of mini-implants submitted to immediate orthodontic loading significantly reduced the tipping to levels similar to those of unloaded mini-implants. Immediate loading further increased the histomorphometric indexes associated with bone formation at the peri-implant region, in both splinted and unsplinted conditions, with no significant differences between the tension and compression regions. Accordingly, within this experimental setting, splinting was found to lessen tipping and mini-implants’ displacement, without affecting the increased bone formation at the peri-implant region, induced by a functional orthodontic load.
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spelling pubmed-102190992023-05-27 Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study Fontes, Joana Martin, Victor Zacharias Resende, Marta Colaço, Bruno Gomes, Pedro de Sousa Amarante, José Manuel J Funct Biomater Article This study aimed to address the stability of orthodontic mini-implants submitted to an immediate orthodontic functional load, in splinted or unsplinted conditions, further characterizing the histomorphometric parameters of the neighboring bone tissue, in an in vivo experimental model. Mini-implants (1.4 × 6.0 mm) were placed in the proximal tibia of New Zealand White rabbits and immediately loaded with a 150 g force. Tissue healing was characterized within 8 weeks. Microtomography was used to assess the mini-implants’ tipping and bone histomorphometric indexes. Loaded implants were evaluated in splinted and unsplinted conditions, with data being compared to that of unloaded mini-implants with the Kruskal–Wallis nonparametric test, followed by Dunn’s multiple comparison tests. The splinting of mini-implants submitted to immediate orthodontic loading significantly reduced the tipping to levels similar to those of unloaded mini-implants. Immediate loading further increased the histomorphometric indexes associated with bone formation at the peri-implant region, in both splinted and unsplinted conditions, with no significant differences between the tension and compression regions. Accordingly, within this experimental setting, splinting was found to lessen tipping and mini-implants’ displacement, without affecting the increased bone formation at the peri-implant region, induced by a functional orthodontic load. MDPI 2023-04-24 /pmc/articles/PMC10219099/ /pubmed/37233349 http://dx.doi.org/10.3390/jfb14050239 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fontes, Joana
Martin, Victor Zacharias
Resende, Marta
Colaço, Bruno
Gomes, Pedro de Sousa
Amarante, José Manuel
Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study
title Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study
title_full Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study
title_fullStr Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study
title_full_unstemmed Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study
title_short Effect of Splinting on Orthodontic Mini-Implant Tipping and Bone Histomorphometric Parameters: An In Vivo Animal Model Study
title_sort effect of splinting on orthodontic mini-implant tipping and bone histomorphometric parameters: an in vivo animal model study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219099/
https://www.ncbi.nlm.nih.gov/pubmed/37233349
http://dx.doi.org/10.3390/jfb14050239
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