Parkin Precipitates on Mitochondria via Aggregation and Autoubiquitination

The loss of the E3 ligase Parkin, in a familial form of Parkinson’s disease, is thought to cause the failure of both the polyubiquitination of abnormal mitochondria and the consequent induction of mitophagy, resulting in abnormal mitochondrial accumulation. However, this has not been confirmed in pa...

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Detalles Bibliográficos
Autores principales: Ardah, Mustafa T., Radwan, Nada, Khan, Engila, Kitada, Tohru, Haque, M Emdadul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219150/
https://www.ncbi.nlm.nih.gov/pubmed/37240373
http://dx.doi.org/10.3390/ijms24109027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219150/
https://www.ncbi.nlm.nih.gov/pubmed/37240373
http://dx.doi.org/10.3390/ijms24109027

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