Cargando…
Dynamic polarization of tumor-associated macrophages and their interaction with intratumoral T cells in an inflamed tumor microenvironment: from mechanistic insights to therapeutic opportunities
Immunotherapy has brought a paradigm shift in the treatment of tumors in recent decades. However, a significant proportion of patients remain unresponsive, largely due to the immunosuppressive tumor microenvironment (TME). Tumor-associated macrophages (TAMs) play crucial roles in shaping the TME by...
Autores principales: | Han, Jiashu, Dong, Luochu, Wu, Mengwei, Ma, Fei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219223/ https://www.ncbi.nlm.nih.gov/pubmed/37251409 http://dx.doi.org/10.3389/fimmu.2023.1160340 |
Ejemplares similares
-
Metabolic Reprogramming Induces Macrophage Polarization in the Tumor Microenvironment
por: Wang, Shilin, et al.
Publicado: (2022) -
Uncoding the interdependency of tumor microenvironment and macrophage polarization: insights from a continuous network approach
por: Avila-Ponce de León, Ugo, et al.
Publicado: (2023) -
Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities
por: Wang, Guoqing, et al.
Publicado: (2022) -
Proteasome-dependent senescent tumor cells mediate immunosuppression through CCL20 secretion and M2 polarization in pancreatic ductal adenocarcinoma
por: Wu, Mengwei, et al.
Publicado: (2023) -
Interferon-Induced Transmembrane Protein 3 Shapes an Inflamed Tumor Microenvironment and Identifies Immuno-Hot Tumors
por: Cai, Yun, et al.
Publicado: (2021)