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Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy

Background: Stereotactic biopsy is a standard procedure for brain biopsy. However, with advances in technology, navigation-guided brain biopsy has become a well-established alternative. Previous studies have shown that frameless stereotactic brain biopsy is as effective and safe as frame-based stere...

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Autores principales: Lim, Dae Hyun, Kim, So Yeon, Na, Young Cheol, Cho, Jin Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219353/
https://www.ncbi.nlm.nih.gov/pubmed/37240878
http://dx.doi.org/10.3390/jpm13050708
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author Lim, Dae Hyun
Kim, So Yeon
Na, Young Cheol
Cho, Jin Mo
author_facet Lim, Dae Hyun
Kim, So Yeon
Na, Young Cheol
Cho, Jin Mo
author_sort Lim, Dae Hyun
collection PubMed
description Background: Stereotactic biopsy is a standard procedure for brain biopsy. However, with advances in technology, navigation-guided brain biopsy has become a well-established alternative. Previous studies have shown that frameless stereotactic brain biopsy is as effective and safe as frame-based stereotactic brain biopsy is. In this study, the authors evaluate the diagnostic yield and complication rate of frameless intracranial biopsy. Materials and Methods: We reviewed data from biopsy performed patients between March 2014 and April 2022. We retrospectively reviewed medical records, including imaging studies. Various intracerebral lesions were biopsied. Diagnostic yield and post-operative complications were compared with those of frame-based stereotactic biopsy. Results: Forty-two frameless navigation-guided biopsy were performed, and the most common pathology was primary central nervous system lymphoma (35.7%), followed by glioblastoma (33.3%), and anaplastic astrocytomas (16.7%), respectively. The diagnostic yield was 100%. Post-operative intracerebral hematoma occurred in 2.4% of cases, but it was not symptomatic. Thirty patients underwent frame-based stereotactic biopsy, and the diagnostic yield was 96.7%. There was no difference in diagnostic rates between two methods (Fisher’s exact test, p = 0.916). Conclusions: Frameless navigation-guided biopsy is as effective as frame-based stereotactic biopsy is, without causing further complications. We consider that frame-based stereotactic biopsy is no longer needed if frameless navigation-guided biopsy is used. A further study will be needed to generalize our results.
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spelling pubmed-102193532023-05-27 Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy Lim, Dae Hyun Kim, So Yeon Na, Young Cheol Cho, Jin Mo J Pers Med Communication Background: Stereotactic biopsy is a standard procedure for brain biopsy. However, with advances in technology, navigation-guided brain biopsy has become a well-established alternative. Previous studies have shown that frameless stereotactic brain biopsy is as effective and safe as frame-based stereotactic brain biopsy is. In this study, the authors evaluate the diagnostic yield and complication rate of frameless intracranial biopsy. Materials and Methods: We reviewed data from biopsy performed patients between March 2014 and April 2022. We retrospectively reviewed medical records, including imaging studies. Various intracerebral lesions were biopsied. Diagnostic yield and post-operative complications were compared with those of frame-based stereotactic biopsy. Results: Forty-two frameless navigation-guided biopsy were performed, and the most common pathology was primary central nervous system lymphoma (35.7%), followed by glioblastoma (33.3%), and anaplastic astrocytomas (16.7%), respectively. The diagnostic yield was 100%. Post-operative intracerebral hematoma occurred in 2.4% of cases, but it was not symptomatic. Thirty patients underwent frame-based stereotactic biopsy, and the diagnostic yield was 96.7%. There was no difference in diagnostic rates between two methods (Fisher’s exact test, p = 0.916). Conclusions: Frameless navigation-guided biopsy is as effective as frame-based stereotactic biopsy is, without causing further complications. We consider that frame-based stereotactic biopsy is no longer needed if frameless navigation-guided biopsy is used. A further study will be needed to generalize our results. MDPI 2023-04-23 /pmc/articles/PMC10219353/ /pubmed/37240878 http://dx.doi.org/10.3390/jpm13050708 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Lim, Dae Hyun
Kim, So Yeon
Na, Young Cheol
Cho, Jin Mo
Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy
title Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy
title_full Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy
title_fullStr Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy
title_full_unstemmed Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy
title_short Navigation Guided Biopsy Is as Effective as Frame-Based Stereotactic Biopsy
title_sort navigation guided biopsy is as effective as frame-based stereotactic biopsy
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219353/
https://www.ncbi.nlm.nih.gov/pubmed/37240878
http://dx.doi.org/10.3390/jpm13050708
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