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Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection

Emerging data suggest an increasing prevalence of persistent symptoms in individuals affected by coronavirus disease-19 (COVID-19). The objective of this study was to determine the relative frequency of altered taste and smell in COVID reinfection (multiple COVID positive tests) and long COVID (one...

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Autores principales: Jaramillo, Mikki, Thyvalikakath, Thankam P., Eckert, George, Srinivasan, Mythily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219407/
https://www.ncbi.nlm.nih.gov/pubmed/37240704
http://dx.doi.org/10.3390/jcm12103598
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author Jaramillo, Mikki
Thyvalikakath, Thankam P.
Eckert, George
Srinivasan, Mythily
author_facet Jaramillo, Mikki
Thyvalikakath, Thankam P.
Eckert, George
Srinivasan, Mythily
author_sort Jaramillo, Mikki
collection PubMed
description Emerging data suggest an increasing prevalence of persistent symptoms in individuals affected by coronavirus disease-19 (COVID-19). The objective of this study was to determine the relative frequency of altered taste and smell in COVID reinfection (multiple COVID positive tests) and long COVID (one COVID positive test). We sent an electronic survey to patients in the Indiana University Health COVID registry with positive COVID test results, querying if they were experiencing symptoms consistent with long COVID including altered chemosensory perceptions. Among the 225 respondents, a greater long COVID burden and COVID reinfection was observed in women. Joint pain was reported as the most common symptom experienced by 18% of individuals in the long COVID cohort. In the COVID reinfection cohort >20% of individuals reported headache, joint pain, and cough. Taste perception worse than pre-COVID was reported by 29% and 42% of individuals in the long COVID and COVID reinfection cohorts, respectively. Smell perception worse than pre-COVID was reported by 37% and 46% of individuals in long COVID and COVID reinfection cohorts, respectively. Further, Chi-square test suggested significant association between pre-COVID severity of taste/smell perception and headache in both cohorts. Our findings highlight the prevalence of persistent chemosensory dysfunction for two years and longer in long COVID and COVID reinfection.
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spelling pubmed-102194072023-05-27 Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection Jaramillo, Mikki Thyvalikakath, Thankam P. Eckert, George Srinivasan, Mythily J Clin Med Article Emerging data suggest an increasing prevalence of persistent symptoms in individuals affected by coronavirus disease-19 (COVID-19). The objective of this study was to determine the relative frequency of altered taste and smell in COVID reinfection (multiple COVID positive tests) and long COVID (one COVID positive test). We sent an electronic survey to patients in the Indiana University Health COVID registry with positive COVID test results, querying if they were experiencing symptoms consistent with long COVID including altered chemosensory perceptions. Among the 225 respondents, a greater long COVID burden and COVID reinfection was observed in women. Joint pain was reported as the most common symptom experienced by 18% of individuals in the long COVID cohort. In the COVID reinfection cohort >20% of individuals reported headache, joint pain, and cough. Taste perception worse than pre-COVID was reported by 29% and 42% of individuals in the long COVID and COVID reinfection cohorts, respectively. Smell perception worse than pre-COVID was reported by 37% and 46% of individuals in long COVID and COVID reinfection cohorts, respectively. Further, Chi-square test suggested significant association between pre-COVID severity of taste/smell perception and headache in both cohorts. Our findings highlight the prevalence of persistent chemosensory dysfunction for two years and longer in long COVID and COVID reinfection. MDPI 2023-05-22 /pmc/articles/PMC10219407/ /pubmed/37240704 http://dx.doi.org/10.3390/jcm12103598 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jaramillo, Mikki
Thyvalikakath, Thankam P.
Eckert, George
Srinivasan, Mythily
Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection
title Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection
title_full Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection
title_fullStr Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection
title_full_unstemmed Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection
title_short Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection
title_sort characteristics of chemosensory perception in long covid and covid reinfection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219407/
https://www.ncbi.nlm.nih.gov/pubmed/37240704
http://dx.doi.org/10.3390/jcm12103598
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