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Novel Allosteric Effectors Targeting Human Transcription Factor TEAD

The Hippo pathway is an evolutionary conserved signaling network involved in several cellular regulatory processes. Dephosphorylation and overexpression of Yes-associated proteins (YAPs) in the Hippo-off state are common in several types of solid tumors. YAP overexpression results in its nuclear tra...

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Detalles Bibliográficos
Autores principales:	Ibrahim, Mayar Tarek, Verkhivker, Gennady M., Misra, Jyoti, Tao, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219411/ https://www.ncbi.nlm.nih.gov/pubmed/37240355 http://dx.doi.org/10.3390/ijms24109009

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