Ileocolonic Healing after Small Ileocecal Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing by Local Mechanisms

Ileocecal resection (ICR) is frequently performed in Crohn’s disease (CD). NOD2 mutations are risk factors for CD. Nod2 knockout (ko) mice show impaired anastomotic healing after extended ICR. We further investigated the role of NOD2 after limited ICR. C57B16/J (wt) and Nod2 ko littermates underwent...

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Detalles Bibliográficos
Autores principales: Witte, Maria B., Saupe, Johannes, Reiner, Johannes, Bannert, Karen, Schafmayer, Clemens, Lamprecht, Georg, Berlin, Peggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219437/
https://www.ncbi.nlm.nih.gov/pubmed/37240707
http://dx.doi.org/10.3390/jcm12103601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219437/
https://www.ncbi.nlm.nih.gov/pubmed/37240707
http://dx.doi.org/10.3390/jcm12103601

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