Cargando…

Aging Changes the Efficacy of Central Urocortin 2 to Induce Weight Loss in Rats

Middle-aged obesity and aging cachexia present healthcare challenges. Central responsiveness to body-weight-reducing mediators, e.g., to leptin, changes during aging in a way, which may promote middle-aged obesity and aging cachexia. Leptin is connected to urocortin 2 (Ucn2), an anorexigenic and hyp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kovács, Dóra K., Eitmann, Szimonetta, Berta, Gergely, Kormos, Viktória, Gaszner, Balázs, Pétervári, Erika, Balaskó, Márta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219457/ https://www.ncbi.nlm.nih.gov/pubmed/37240340 http://dx.doi.org/10.3390/ijms24108992

Ejemplares similares

Assessment of clinical data on urocortins and their therapeutic potential in cardiovascular diseases: A systematic review and meta‐analysis
por: Kovács, Dóra K., et al.
Publicado: (2021)

Maternal overnutrition impairs offspring's insulin sensitivity: A systematic review and meta‐analysis
por: Eitmann, Szimonetta, et al.
Publicado: (2020)

Fluoxetine treatment supports predictive validity of the three hit model of depression in male PACAP heterozygous mice and underpins the impact of early life adversity on therapeutic efficacy
por: Gaszner, Tamás, et al.
Publicado: (2022)

Neurodegeneration in the centrally-projecting Edinger–Westphal nucleus contributes to the non-motor symptoms of Parkinson’s disease in the rat
por: Ujvári, Balázs, et al.
Publicado: (2022)

Transient receptor potential ankyrin 1 ion channel expressed by the Edinger-Westphal nucleus contributes to stress adaptation in murine model of posttraumatic stress disorder
por: Konkoly, János, et al.
Publicado: (2022)

Downregulation of PACAP and the PAC1 Receptor in the Basal Ganglia, Substantia Nigra and Centrally Projecting Edinger–Westphal Nucleus in the Rotenone model of Parkinson’s Disease
por: Fehér, Máté, et al.
Publicado: (2023)

Maternal overnutrition elevates offspring’s blood pressure—A systematic review and meta‐analysis
por: Eitmann, Szimonetta, et al.
Publicado: (2022)

Functionally active TRPA1 ion channel is downregulated in peptidergic neurons of the Edinger-Westphal nucleus upon acute alcohol exposure
por: Al-Omari, Ammar, et al.
Publicado: (2023)

Epigenetic and Neuronal Activity Markers Suggest the Recruitment of the Prefrontal Cortex and Hippocampus in the Three-Hit Model of Depression in Male PACAP Heterozygous Mice
por: Gaszner, Tamás, et al.
Publicado: (2022)

The Role of TRPA1 Channels in the Central Processing of Odours Contributing to the Behavioural Responses of Mice
por: Konkoly, János, et al.
Publicado: (2021)

Epineural Methylene Blue Injection May Aid Localization of Digital Nerves in Dupuytren's Surgery
por: Szabó, Tamás, et al.
Publicado: (2022)

Corticotropin-Releasing Factor-Producing Cells in the Paraventricular Nucleus of the Hypothalamus and Extended Amygdala Show Age-Dependent FOS and FOSB/DeltaFOSB Immunoreactivity in Acute and Chronic Stress Models in the Rat
por: Kovács, László Á., et al.
Publicado: (2019)

The onset of daily torpor is regulated by the same low body mass in lean mice and in mice with diet-induced obesity
por: Solymár, Margit, et al.
Publicado: (2015)

Peptidergic neurons of the Edinger–Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in humans who died by suicide
por: Kormos, Viktória, et al.
Publicado: (2022)

Linking stress with urocortin in rats
por: Balraj, Manikandan, et al.
Publicado: (2023)

Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure
por: Stirrat, Colin G., et al.
Publicado: (2016)

Human Somatostatin SST(4) Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization
por: Nemes, Balázs, et al.
Publicado: (2021)

Urocortin stimulates the ERK1/2 signaling pathway and the proliferation of HeLa cells via CRF receptor 1
por: Balogh, Bálint, et al.
Publicado: (2023)

Age-Dependent FOSB/ΔFOSB Response to Acute and Chronic Stress in the Extended Amygdala, Hypothalamic Paraventricular, Habenular, Centrally-Projecting Edinger-Westphal, and Dorsal Raphe Nuclei in Male Rats
por: Kovács, László Ákos, et al.
Publicado: (2022)

Urocortins in the mammalian endocrine system
por: Squillacioti, Caterina, et al.
Publicado: (2019)

The Role of Urocortins in Intracerebral Hemorrhage
por: Choy, Ker Woon, et al.
Publicado: (2020)

Exploring the Role of Urocortin in Osteoporosis
por: Ismail, Omar M, et al.
Publicado: (2023)

Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal
por: Giamouridis, Dimosthenis, et al.
Publicado: (2018)

Regulation and Roles of Urocortins in the Vascular System
por: Kageyama, Kazunori, et al.
Publicado: (2012)

New targets of urocortin-mediated cardioprotection
por: Barry, Seán P, et al.
Publicado: (2010)

Urocortin Role in Ischemia Cardioprotection and the Adverse Cardiac Remodeling
por: Calderón-Sánchez, Eva M., et al.
Publicado: (2021)

Intranasal Delivery of a Methyllanthionine-Stabilized Galanin Receptor-2-Selective Agonist Reduces Acute Food Intake
por: Kuipers, Anneke, et al.
Publicado: (2021)

Urocortin-1 within the Centrally-Projecting Edinger-Westphal Nucleus Is Critical for Ethanol Preference
por: Giardino, William J., et al.
Publicado: (2011)

Changes in Musculoskeletal System and Metabolism in Osteoporotic Rats Treated With Urocortin
por: Saul, Dominik, et al.
Publicado: (2019)

Regulation of gonadotropins by corticotropin-releasing factor and urocortin
por: Kageyama, Kazunori
Publicado: (2013)

Urocortin Expression in Endometriosis: A Systematic Review
por: Pergialiotis, Vasilios, et al.
Publicado: (2019)

Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey Petromyzon marinus
por: Sobrido-Cameán, Daniel, et al.
Publicado: (2021)

Thermoregulatory effect of alarin, a new member of the galanin peptide family
por: Mikó, Alexandra, et al.
Publicado: (2014)

Sandblasting reduces dental implant failure rate but not marginal bone level loss: A systematic review and meta-analysis
por: Czumbel, László Márk, et al.
Publicado: (2019)

Metformin induces significant reduction of body weight, total cholesterol and LDL levels in the elderly – A meta-analysis
por: Solymár, Margit, et al.
Publicado: (2018)

Vascular Effects of Urocortins 2 and 3 in Healthy Volunteers
por: Venkatasubramanian, Sowmya, et al.
Publicado: (2013)

Urocortin Neuropeptide Levels Are Impaired in the PBMCs of Overweight Children
por: Kavalakatt, Sina, et al.
Publicado: (2022)

Circulating levels of urocortin neuropeptides are impaired in children with overweight
por: Kavalakatt, Sina, et al.
Publicado: (2022)

Expression Patterns of the Neuropeptide Urocortin 3 and Its Receptor CRFR2 in the Mouse Central Auditory System
por: Pagella, Sara, et al.
Publicado: (2021)

Transversus Abdominis Plane Block Appears to Be Effective and Safe as a Part of Multimodal Analgesia in Bariatric Surgery: a Meta-analysis and Systematic Review of Randomized Controlled Trials
por: Földi, Mária, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dgh3l2se0e9u0514v96qovf6vb