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Human Umbilical Cord Mesenchymal Stem Cells Protect against Renal Ischemia-Reperfusion Injury by Secreting Extracellular Vesicles Loaded with miR-148b-3p That Target Pyruvate Dehydrogenase Kinase 4 to Inhibit Endoplasmic Reticulum Stress at the Reperfusion Stages

Renal ischemia-reperfusion (I/R) injury is a leading cause of acute kidney injury (AKI), with high mortality. Recent studies have reported that human umbilical cord mesenchymal stem cells (HucMSCs) play an important role in repairing organ and tissue injuries because of their unique characteristics....

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Detalles Bibliográficos
Autores principales: Shi, Wei, Zhou, Xiang, Li, Xinyuan, Peng, Xiang, Chen, Guo, Li, Yang, Zhang, Chunlin, Yu, Haitao, Feng, Zhenwei, Gou, Xin, Fan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219505/
https://www.ncbi.nlm.nih.gov/pubmed/37240246
http://dx.doi.org/10.3390/ijms24108899