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DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in MYCN-Amplified Neuroblastoma IMR32 Cells

Identifying the vulnerability of altered DNA repair machinery that displays synthetic lethality with MYCN amplification is a therapeutic rationale in unfavourable neuroblastoma. However, none of the inhibitors for DNA repair proteins are established as standard therapy in neuroblastoma. Here, we inv...

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Detalles Bibliográficos
Autores principales:	Ando, Kiyohiro, Suenaga, Yusuke, Kamijo, Takehiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219512/ https://www.ncbi.nlm.nih.gov/pubmed/37240360 http://dx.doi.org/10.3390/ijms24109012

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