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A Small Scale Optically Pumped Fetal Magnetocardiography System

Introduction: Fetal magnetocardiography (fMCG) is considered the best technique for diagnosis of fetal arrhythmia. It is superior to more widely used methods such as fetal, fetal electrocardiography, and cardiotocography for evaluation of fetal rhythm. The combination of fMCG and fetal echocardiogra...

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Autores principales: Wurm, David, Ewert, Peter, Fierlinger, Peter, Wakai, Ronald T., Wallner, Verena, Wunderl, Lena, Wacker-Gußmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219566/
https://www.ncbi.nlm.nih.gov/pubmed/37240486
http://dx.doi.org/10.3390/jcm12103380
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author Wurm, David
Ewert, Peter
Fierlinger, Peter
Wakai, Ronald T.
Wallner, Verena
Wunderl, Lena
Wacker-Gußmann, Annette
author_facet Wurm, David
Ewert, Peter
Fierlinger, Peter
Wakai, Ronald T.
Wallner, Verena
Wunderl, Lena
Wacker-Gußmann, Annette
author_sort Wurm, David
collection PubMed
description Introduction: Fetal magnetocardiography (fMCG) is considered the best technique for diagnosis of fetal arrhythmia. It is superior to more widely used methods such as fetal, fetal electrocardiography, and cardiotocography for evaluation of fetal rhythm. The combination of fMCG and fetal echocardiography can provide a more comprehensive evaluation of fetal cardiac rhythm and function than is currently possible. In this study, we demonstrate a practical fMCG system based on optically pumped magnetometers (OPMs). Methods: Seven pregnant women with uncomplicated pregnancies underwent fMCG at 26–36 weeks’ gestation. The recordings were made using an OPM-based fMCG system and a person-sized magnetic shield. The shield is much smaller than a shielded room and provides easy access with a large opening that allows the pregnant woman to lie comfortably in a prone position. Results: The data show no significant loss of quality compared to data acquired in a shielded room. Measurements of standard cardiac time intervals yielded the following results: PR = 104 ± 6 ms, QRS = 52.6 ± 1.5 ms, and QTc = 387 ± 19 ms. These results are compatible with those from prior studies performed using superconducting quantum interference device (SQUID) fMCG systems. Conclusions: To our knowledge, this is the first European fMCG device with OPM technology commissioned for basic research in a pediatric cardiology unit. We demonstrated a patient-friendly, comfortable, and open fMCG system. The data yielded consistent cardiac intervals, measured from time-averaged waveforms, compatible with published SQUID and OPM data. This is an important step toward making the method widely accessible.
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spelling pubmed-102195662023-05-27 A Small Scale Optically Pumped Fetal Magnetocardiography System Wurm, David Ewert, Peter Fierlinger, Peter Wakai, Ronald T. Wallner, Verena Wunderl, Lena Wacker-Gußmann, Annette J Clin Med Communication Introduction: Fetal magnetocardiography (fMCG) is considered the best technique for diagnosis of fetal arrhythmia. It is superior to more widely used methods such as fetal, fetal electrocardiography, and cardiotocography for evaluation of fetal rhythm. The combination of fMCG and fetal echocardiography can provide a more comprehensive evaluation of fetal cardiac rhythm and function than is currently possible. In this study, we demonstrate a practical fMCG system based on optically pumped magnetometers (OPMs). Methods: Seven pregnant women with uncomplicated pregnancies underwent fMCG at 26–36 weeks’ gestation. The recordings were made using an OPM-based fMCG system and a person-sized magnetic shield. The shield is much smaller than a shielded room and provides easy access with a large opening that allows the pregnant woman to lie comfortably in a prone position. Results: The data show no significant loss of quality compared to data acquired in a shielded room. Measurements of standard cardiac time intervals yielded the following results: PR = 104 ± 6 ms, QRS = 52.6 ± 1.5 ms, and QTc = 387 ± 19 ms. These results are compatible with those from prior studies performed using superconducting quantum interference device (SQUID) fMCG systems. Conclusions: To our knowledge, this is the first European fMCG device with OPM technology commissioned for basic research in a pediatric cardiology unit. We demonstrated a patient-friendly, comfortable, and open fMCG system. The data yielded consistent cardiac intervals, measured from time-averaged waveforms, compatible with published SQUID and OPM data. This is an important step toward making the method widely accessible. MDPI 2023-05-10 /pmc/articles/PMC10219566/ /pubmed/37240486 http://dx.doi.org/10.3390/jcm12103380 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Wurm, David
Ewert, Peter
Fierlinger, Peter
Wakai, Ronald T.
Wallner, Verena
Wunderl, Lena
Wacker-Gußmann, Annette
A Small Scale Optically Pumped Fetal Magnetocardiography System
title A Small Scale Optically Pumped Fetal Magnetocardiography System
title_full A Small Scale Optically Pumped Fetal Magnetocardiography System
title_fullStr A Small Scale Optically Pumped Fetal Magnetocardiography System
title_full_unstemmed A Small Scale Optically Pumped Fetal Magnetocardiography System
title_short A Small Scale Optically Pumped Fetal Magnetocardiography System
title_sort small scale optically pumped fetal magnetocardiography system
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219566/
https://www.ncbi.nlm.nih.gov/pubmed/37240486
http://dx.doi.org/10.3390/jcm12103380
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