Cargando…

Systematic discovery of transcription factors that improve hPSC-derived cardiomyocyte maturation via temporal analysis of bioengineered cardiac tissues

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have the potential to become powerful tools for disease modeling, drug testing, and transplantation; however, their immaturity limits their applications. Transcription factor (TF) overexpression can improve hPSC-CM maturity, but identifyi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Aditya, He, Starry, Mali, Prashant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AIP Publishing LLC 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219684/ https://www.ncbi.nlm.nih.gov/pubmed/37252678 http://dx.doi.org/10.1063/5.0137458

Ejemplares similares

Transfection of hPSC-Cardiomyocytes Using Viafect™ Transfection Reagent
por: Bodbin, Sara E., et al.
Publicado: (2020)

The cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes
por: Poon, Ellen Ngar-Yun, et al.
Publicado: (2020)

A net-shaped multicellular formation facilitates the maturation of hPSC-derived cardiomyocytes through mechanical and electrophysiological stimuli
por: Liu, Taoyan, et al.
Publicado: (2018)

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation
por: Heller, Sandra, et al.
Publicado: (2021)

Ultrasensitive and rapid quantification of rare tumorigenic stem cells in hPSC-derived cardiomyocyte populations
por: Wang, Zongjie, et al.
Publicado: (2020)

hPSC-derived organoids: models of human development and disease
por: Frum, Tristan, et al.
Publicado: (2020)

hPSC-derived lung organoids: Potential opportunities and challenges
por: Du, Xiaoli, et al.
Publicado: (2023)

Engineering induction of singular neural rosette emergence within hPSC-derived tissues
por: Knight, Gavin T, et al.
Publicado: (2018)

Microscale grooves regulate maturation development of hPSC‐CMs by the transient receptor potential channels (TRP channels)
por: Liu, Taoyan, et al.
Publicado: (2021)

Correction to: hPSC-derived organoids: models of human development and disease
por: Frum, Tristan, et al.
Publicado: (2020)

Advances in hPSC expansion towards therapeutic entities: A review
por: Tannenbaum, Shelly E., et al.
Publicado: (2022)

Perspectives on the cost of goods for hPSC banks for manufacture of cell therapies
por: Kim, Jung-Hyun, et al.
Publicado: (2022)

Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format
por: Mannhardt, Ingra, et al.
Publicado: (2020)

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)
por: Sala, Luca, et al.
Publicado: (2017)

Assessing Cell Competition in Human Pluripotent Stem Cell (hPSC) Cultures
por: Price, Christopher J., et al.
Publicado: (2022)

Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy
por: Upadhya, Dinesh, et al.
Publicado: (2022)

An hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection
por: Lang, Jianshe, et al.
Publicado: (2018)

The endothelium, a key actor in organ development and hPSC-derived organoid vascularization
por: Vargas-Valderrama, Alejandra, et al.
Publicado: (2020)

Human pluripotent stem cell (hPSC) and organoid models of autism: opportunities and limitations
por: Kilpatrick, Savannah, et al.
Publicado: (2023)

Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation
por: Taga, Shiori, et al.
Publicado: (2023)

CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of β(2)AR in isogenic hPSC-derived cardiomyocytes
por: Kondrashov, Alexander, et al.
Publicado: (2020)

Maturing iPSC-Derived Cardiomyocytes
por: Tang, Bor Luen
Publicado: (2020)

High-throughput 3D screening for differentiation of hPSC-derived cell therapy candidates
por: Muckom, Riya, et al.
Publicado: (2020)

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease
por: Coccia, Elena, et al.
Publicado: (2021)

Comparative microelectrode array data of the functional development of hPSC-derived and rat neuronal networks
por: Kapucu, Fikret Emre, et al.
Publicado: (2022)

Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids
por: Rao, Kavitha S., et al.
Publicado: (2022)

FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision
por: Hackland, James O.S., et al.
Publicado: (2019)

Transplantation of hPSC-derived pericyte-like cells promotes functional recovery in ischemic stroke mice
por: Sun, Jiaqi, et al.
Publicado: (2020)

Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation
por: Jo, Hye-Yeong, et al.
Publicado: (2020)

Long-term corneal recovery by simultaneous delivery of hPSC-derived corneal endothelial precursors and nicotinamide
por: Li, Zongyi, et al.
Publicado: (2022)

Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
por: Halloin, Caroline, et al.
Publicado: (2019)

Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
por: Halloin, Caroline, et al.
Publicado: (2019)

Bioengineering Clinically Relevant Cardiomyocytes and Cardiac Tissues from Pluripotent Stem Cells
por: James, Emma Claire, et al.
Publicado: (2021)

Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes
por: Imaizumi, Kent, et al.
Publicado: (2015)

Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity
por: Moya, Noel, et al.
Publicado: (2014)

Sulfated Alginate Reduces Pericapsular Fibrotic Overgrowth on Encapsulated cGMP-Compliant hPSC-Hepatocytes in Mice
por: Syanda, Adam M., et al.
Publicado: (2022)

Bi-potential hPSC-derived Müllerian duct-like cells for full-thickness and functional endometrium regeneration
por: Gong, Lin, et al.
Publicado: (2022)

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Sun, Xuetao, et al.
Publicado: (2017)

Cardiac fibroblast-derived VCAM-1 enhances cardiomyocyte proliferation for fabrication of bioengineered cardiac tissue
por: Iwamiya, Takahiro, et al.
Publicado: (2016)

iPSC-Derived Cardiomyocytes in Inherited Cardiac Arrhythmias: Pathomechanistic Discovery and Drug Development
por: Simons, Eline, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_smlembp37f8g1sov0h3ad6robp