Oxidization of optic atrophy 1 cysteines occurs during heart ischemia-reperfusion and amplifies cell death by oxidative stress

During cardiac ischemia-reperfusion, excess reactive oxygen species can damage mitochondrial, cellular and organ function. Here we show that cysteine oxidation of the mitochondrial protein Opa1 contributes to mitochondrial damage and cell death caused by oxidative stress. Oxy-proteomics of ischemic-...

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Detalles Bibliográficos
Autores principales: Semenzato, Martina, Kohr, Mark J., Quirin, Charlotte, Menabò, Roberta, Alanova, Petra, Alan, Lukas, Pellattiero, Anna, Murphy, Elizabeth, Di Lisa, Fabio, Scorrano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220262/
https://www.ncbi.nlm.nih.gov/pubmed/37224696
http://dx.doi.org/10.1016/j.redox.2023.102755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220262/
https://www.ncbi.nlm.nih.gov/pubmed/37224696
http://dx.doi.org/10.1016/j.redox.2023.102755

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