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Association of TIM-3 checkpoint receptor expression on T cells with treatment-free remission in chronic myeloid leukemia

Dysregulation of immune-checkpoint receptors has been reported at diagnosis of chronic myeloid leukemia (CML), however, their role in the maintenance of remission after tyrosine kinase inhibitor (TKI) cessation is unclear. We assessed programmed cell death-1 (PD-1), T-cell immunoglobulin, and mucin-...

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Detalles Bibliográficos
Autores principales: Irani, Yazad D., Kok, Chung H., Clarson, Jade, Shanmuganathan, Naranie, Branford, Susan, Yeung, David T., Ross, David M., Hughes, Timothy P., Yong, Agnes S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220272/
https://www.ncbi.nlm.nih.gov/pubmed/36622326
http://dx.doi.org/10.1182/bloodadvances.2022008854