Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection

Amphotericin B is the currently recommended therapy for Malassezia invasive infection (MII), but this drug requires intravenous administration and is associated with significant toxicity. The role of broad-spectrum azoles in managing MII is not clear. We describe two cases of MII due to M. pachyderm...

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Autores principales: Shah, Sunish, Nguyen, M. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220303/
https://www.ncbi.nlm.nih.gov/pubmed/37251705
http://dx.doi.org/10.1016/j.mmcr.2023.05.002
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author Shah, Sunish
Nguyen, M. Hong
author_facet Shah, Sunish
Nguyen, M. Hong
author_sort Shah, Sunish
collection PubMed
description Amphotericin B is the currently recommended therapy for Malassezia invasive infection (MII), but this drug requires intravenous administration and is associated with significant toxicity. The role of broad-spectrum azoles in managing MII is not clear. We describe two cases of MII due to M. pachydermatis and M. furfur that were successfully treated with posaconazole and reviewed the literature to assess the position of posaconazole in treating MII.
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spelling pubmed-102203032023-05-28 Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection Shah, Sunish Nguyen, M. Hong Med Mycol Case Rep Case Report Amphotericin B is the currently recommended therapy for Malassezia invasive infection (MII), but this drug requires intravenous administration and is associated with significant toxicity. The role of broad-spectrum azoles in managing MII is not clear. We describe two cases of MII due to M. pachydermatis and M. furfur that were successfully treated with posaconazole and reviewed the literature to assess the position of posaconazole in treating MII. Elsevier 2023-05-12 /pmc/articles/PMC10220303/ /pubmed/37251705 http://dx.doi.org/10.1016/j.mmcr.2023.05.002 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Shah, Sunish
Nguyen, M. Hong
Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection
title Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection
title_full Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection
title_fullStr Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection
title_full_unstemmed Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection
title_short Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection
title_sort potential role of broad-spectrum azoles as therapy for malasezzia bloodstream infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220303/
https://www.ncbi.nlm.nih.gov/pubmed/37251705
http://dx.doi.org/10.1016/j.mmcr.2023.05.002
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AT nguyenmhong potentialroleofbroadspectrumazolesastherapyformalasezziabloodstreaminfection

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