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Studying how administration route and dose regulates antibody generation against LNPs for mRNA delivery with single-particle resolution

Following the recent approval of both siRNA- and mRNA-based therapeutics, nucleic acid therapies are considered a game changer in medicine. Their envisioned widespread use for many therapeutic applications with an array of cellular target sites means that various administration routes will be employ...

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Detalles Bibliográficos
Autores principales:	Münter, Rasmus, Christensen, Esben, Andresen, Thomas L., Larsen, Jannik B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220314/ https://www.ncbi.nlm.nih.gov/pubmed/37251983 http://dx.doi.org/10.1016/j.omtm.2023.05.008

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