Development and validation of an LC-MS/MS method to quantify ceftaroline in microdialysate samples from plasma and brain: Application to a preclinical pharmacokinetic investigation

A bioanalytical LC–MS/MS method was developed and validated to determine ceftaroline in microdialysate samples from plasma and brain. Ceftaroline was separated using a C18 column and a mobile phase consisting of water and acetonitrile, both with 5 mM of ammonium formate and acid formic 0.1%, eluted...

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Detalles Bibliográficos
Autores principales: Helfer, Victória Etges, Dias, Bruna Bernar, Lock, Graziela de Araújo, Tomaszewski, Caroline Andrade, Barnet, Lucas Suchecki, Barreto, Fabiano, Zavascki, Alexandre Prehn, Araújo, Bibiana Verlindo de, Dalla Costa, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220404/
https://www.ncbi.nlm.nih.gov/pubmed/37251463
http://dx.doi.org/10.1016/j.heliyon.2023.e16564

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